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Can Fam Physician
Vol. 53, No. 12, December 2007, pp.2132 - 2138
Copyright © 2007 by The College of Family Physicians of Canada
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Research

Maternal outcomes of cesarean sections

Do generalists’ patients have different outcomes than specialists’ patients?

Kris Aubrey-Bassler, MD MSc
Lecturer in Family Medicine at the Northern Ontario School of Medicine in Marathon, Ont

Sarah Newbery, MD CCFP FCFP
Associate Professor of Family Medicine at the Northern Ontario School of Medicine

Len Kelly, MD MClSc CCFP FCFP
Associate Professor of Family Medicine at the Northern Ontario School of Medicine and an Associate Clinical Professor of Family Medicine at McMaster University in Sioux Lookout, Ont

Bruce Weaver, MSc
Assistant Professor of Biostatistics in the Human Sciences Division at the Northern Ontario School of Medicine

Scott Wilson, MD CCFP
Family physician in Marathon

Correspondence to: Dr Aubrey-Bassler, Marathon Family Medicine Team, Box 300, Marathon, ON P0T 2E0; telephone 807 229–3243; fax 807 229–2672; e-mail Kris.Aubrey{at}normed.ca

The discipline of family medicine struggles to meet the needs of women in labour in Canada. Many programs have instituted extra training of varied length for specialized obstetric skills. In many small community hospitals, family physicians and GPs with additional training already offer advanced maternity care, such as cesarean sections.1 While studies of rural obstetric care suggest that neonatal outcomes of GP-managed cesarean sections are similar to those of specialist-managed cesarean sections,2 there is little evidence in the literature on maternal outcomes. There is evidence that suggests that GP-managed patients have outcomes comparable to accepted standards; however, the studies from which this evidence comes are limited by methodologic problems.3,4

We sought to determine the safety of GP-managed cesarean sections by doing a retrospective study using specialists’ patients as the reference group. To adjust for differences in patient populations, we matched GPs’ cases to those of specialists’ for comorbid diagnoses that might have influenced surgical outcomes. Neonatal outcomes were not available in the data set we accessed.


   METHOD
TOP
 METHOD
RESULTS
 DISCUSSION
 Footnotes
 Acknowledgment
 References
 
Data on all cesarean sections performed during the fiscal years 1990 to 2000 were accessed in the Canadian Institute for Health Information’s Discharge Abstracts Database (DAD) for provinces where most GPs performing cesarean sections in Canada practise: Alberta, British Columbia, Ontario, and Saskatchewan.

A questionnaire asking about surgical training was distributed to GPs performing cesarean sections. Physicians were enrolled in the study if they had 1 year or less of surgical training beyond their family or general practice training in order to exclude highly trained GPs who had had surgical training approaching that of specialists. Informed consent was obtained from each of these GP surgeons and their hospitals. Consent from specialists was not necessary because all identifying information in the DAD was encrypted, and the database included all cesarean sections done by specialists during the 10-year period. Approval for the study was received from the Lakehead University Research Ethics Board.

Case matching
Each case managed by a consenting GP was extracted and matched for noniatrogenic comorbid diagnoses to 3 cases managed by specialists. Matching was 1 to 3 in order to increase statistical power. Cases were grouped into 5-year categories by patient age and 3-year categories by date of cesarean section, then matched within these categories. Diagnoses were included if they were likely the indication for proceeding to cesarean section or if they were thought to adversely affect maternal outcomes5 (Table 16,7).* Maternal obstetric history (with the exception of whether or not mothers had had previous cesarean sections), body mass index, and socioeconomic status were not available in the DAD.

Outcome measures
There were 2 primary outcome measures: the composite of death and major morbidity possibly attributable to surgery (major surgical morbidity), and the composite of all major morbidity (Table 26,7).* Ileus and bowel obstruction diagnoses typically had a length of hospital stay similar to the mean, suggesting minimal morbidity. They were included, however, when they contributed to a prolonged length of stay (mean length of stay plus 2 standard deviations).

Secondary outcomes included length of hospital stay, postpartum transfer to another acute care institution, surgical error (Table 36), and the need for blood transfusion. For patients of GPs transferred postpartum directly from the treating facility to another acute care hospital, we accessed the database record at the receiving institution, where possible, and adjusted data as appropriate. When length of stay at the receiving institution was unavailable, data on these transferred patients were excluded from the final analysis.


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  		Table 3 International Classification of Diseases, 9th Revision,6 (ICD 9) and Canadian Classification of Diagnostic, Therapeutic, and Surgical Procedure7 (CCP) codes for outcomes of surgical error

 
Statistics
Given the relatively small number of GPs and the possibility of clustering of outcomes by GP, a GP surgeon variable was incorporated into the regression model. As this adjustment did not affect any results, we present only unadjusted data in the Results section. For conditional logistic regression data, we give the Wald P value. Differences were considered significant if P < .05. Data are presented as means with standard deviations or odds ratios with 95% confidence intervals where appropriate. Conditional logistic regression analyses were done using Stata version 8.2. Length of hospital stay for the 3 specialist cases within each match were averaged, and these data were then compared using paired t tests in SPSS version 11.5.0.


   RESULTS
TOP
 METHOD
 RESULTS
DISCUSSION
 Footnotes
 Acknowledgment
 References
 
Fifty-two surveys were mailed to GPs; response rate was 58%. Fifteen GPs were excluded: 7 had received more than 1 year of surgical training; 5 had not done any cesarean sections during the study period; 1 was not a GP surgeon; 1 replied too late; and 1 did not get hospital approval. Characteristics of the 15 GPs included are shown in Table 4.


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  		Table 4 Characteristics of general practitioner surgeons

 
Data were retrieved for a total of 498 979 cesarean sections, 1509 of which were performed by the GPs in this study. Among the 1509 GP cases, 61 could not be matched to 3 specialist cases and were excluded. Primary outcomes for these excluded cases were not significantly different from outcomes of the remaining GP cases (data not shown). Each of the remaining 1448 GP cases was matched to 3 specialist cases, so 5792 cases were included in the subsequent analysis.

Of all the cesarean sections performed by specialists, 183 (4.2%) were done by general surgeons, and the remainder were done by obstetricians. Mean age of patients was 26.7 years in the GP group and 26.8 years in the specialist group. Other relevant group characteristics were included in the matching algorithm, so the rates were identical (Table 16,7).

Data on rates of composite major morbidity variables, blood transfusions, surgical errors, and patient transfers are shown in Table 5. When the International Classification of Diseases, 9th Revision,6 code for major puerperal infection (endometritis, peritonitis, pyemia, salpingitis, and septicemia) was removed from the 2 composite major morbidity variables, differences in outcomes were non-significant (1.5% vs 1.1% for all major morbidity and 1.0% vs 0.8% for major surgical morbidity). Length of hospital stay was shorter in the specialist group than in the GP group (4.9 vs 5.2 days, mean difference 0.23 days, 95% confidence interval for difference 0.06 to 0.39, P = .006). Results of other secondary outcome analyses are shown in Tables 5, 6, and 7.


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  		Table 5 Primary and secondary outcomes

 

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  		Table 6 Rates of diagnoses of major surgical morbidity outcomes by study group

 

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  		Table 7 Rates of diagnoses of all major morbidity outcomes by study group

 

   DISCUSSION
TOP
 METHOD
 RESULTS
 DISCUSSION
Footnotes
 Acknowledgment
 References
 
Comparing outcomes of GP-managed and specialist-managed patients
Previous studies have compared the outcomes of generalist-managed cesarean sections with referenced rates of complications in the literature3 or with the outcomes of unmatched specialist-managed cases.4 This is the first study to do a simultaneous comparison with a set of equivalent patients. Perhaps the most striking finding here is the low rates of all major morbidity and major surgical morbidity observed in both groups, despite the comprehensive definitions of these outcomes.

General practitioners are likely to transfer high-risk patients to specialist centres. Using our matching algorithm, we therefore selected low-risk specialist-managed patients. The complication rates we have calculated should be generalizable to low-risk patient populations.

We found a slight but significantly higher rate of adverse maternal outcomes in the GP group (P = .009). Although it might be inferred that the GPs themselves are responsible for this, other factors help explain the difference. The surgical error variable includes the typical surgical mistakes often observed during cesarean sections. The observation that rates of both surgical error and the need for blood transfusion were similar in the 2 groups suggests that surgical technique does not explain the differences observed in major morbidity outcomes. Other factors, such as socioeconomic status, maternal medical and obstetric history, duration of ruptured membranes, and anesthetic technique were not available in the data set and might help explain these differences.

All the GPs in our study practised in rural or semirural areas, whereas the specialists practised in larger, urban centres. This could have affected our data in several ways: first, socioeconomic status tends to be lower8 and maternal parity higher in rural areas, 2 factors that have been shown to affect neonatal and likely maternal outcomes adversely.9,10 Second, limited access to obstetric care in rural areas has been shown to affect obstetric outcomes negatively.11–13 Third, staff in small rural hospitals might be less familiar with delivery and operating room best practices than staff in large centres where specialists tend to practise.

Reasons for different rates of adverse outcomes
The observation that the removal of major puerperal infection from the composite morbidity variables made the differences in outcomes non-significant suggests several explanations for the differences between groups. Most obvious, differences in infection rates suggest differences in sterility practices between family physicians and specialists or their hospitals. This hypothesis is supported by a previous study of cesarean sections performed by GPs and specialists that noted a difference in the rates of positive cultures and antibiotic treatment.4 This information was not available in the DAD. Second, it is commonly believed that the obstetric patients of family physicians have a lower rate of cesarean sections. If true, this implies that family physicians’ patients labour longer (family physicians wait longer before proceeding to cesarean section during which time some women deliver vaginally), a factor known to increase the rate of postpartum infection.14 Other reasons GP patients labour longer could include delays associated with calling in operating room teams or surgeons, which likely takes longer in the smaller hospitals where GPs practise. While the difference between the 2 groups is statistically significant, the infection rates of 1.6% for GPs and 0.8% for specialists is likely of little clinical relevance, as typical infection rates after cesarean section approach 10%.15

We noted a significantly shorter length of hospital stay for specialist surgeons’ patients (P = .006). The clinical significance of the 5.5-hour difference is unclear, but we are unable to exclude the possibility that it represents a difference in rate of recovery from surgery.

The rate of patient transfer to an acute care hospital following cesarean section was substantially higher among patients of GPs than among patients of specialists. Although this might imply a higher rate of complications requiring transfer for care by another physician, it could also be explained by the geographic differences between where the groups practise. Specialists practise in larger centres with greater access to other specialists where interdisciplinary referrals for maternity care would not require patients to transfer. In addition, mothers are typically transferred along with their neonates when the babies require specialist consultation, so more mothers are transferred from smaller hospitals than from specialist hospitals. We did not have access to DAD data on neonates, so we were unable to determine the rate of neonatal indications for transfer, and we did not analyze maternal indications for transfer.

Studies comparing outcomes of procedures by volume of treating physician or hospital show, albeit inconsistently, that higher volumes are associated with better outcomes, as one might expect.16 The best evidence for this volume-to-outcome relationship comes from highly technical procedures, such as pancreatectomy, esophagectomy, and elective abdominal aortic aneurysm repair. Analysis of the volume-to-outcome relationship for obstetrics has focused almost exclusively on neonatal rather than maternal outcomes.17 One study examining all maternal (vaginal and cesarean section) outcomes from administrative data suggested that there is a threshold effect, with hospital outcomes dependent on a minimum number of deliveries per year.18 Analysis of chart-level data19,20 does not support this conclusion. The effect of these findings on our results is uncertain given the range of experience of the GPs in this study. Previous studies have suggested that GPs record clinical findings more completely than specialists do.3,4 This might have biased our results against GPs due to their more thorough reporting of adverse outcomes.

Limitations
Possible inaccuracies in the database7,21–24 represent the most important limitation of studies of this type. As discussed above, we matched patients in this study to overcome referral bias whereby patients with comorbidity are identified antenatally and preferentially referred to specialists for management. Although we attempted to be as thorough as possible in the matching algorithm, including multiple comorbid diagnoses as well as previous cesarean sections, the number of previous cesarean sections received by each patient was not coded in the DAD. The number of patients with multiple previous cesarean sections is likely relatively small, however, and although this factor can affect neonatal outcomes, it likely has a minimal effect on maternal outcomes.25

Conclusion
Both generalists and specialists offer cesarean sections with a low rate of maternal complications. Patients of GPs with a mean of 4 months’ surgical training have some differences in outcomes compared with patients of specialists. Factors other than the specialty of the care provider might be responsible for these differences. Further research could examine the adverse health and other effects associated with not having obstetric care close to home,26 as well as the outcomes of women and neonates who require intrapartum transfer for cesarean section when this service is not offered at their local hospitals.



   EDITOR’S KEY POINTS
 
  • While studies of rural obstetric care suggest that neonatal outcomes of cesarean sections managed by general practitioners are equivalent to those managed by specialists, there is little documentation of maternal outcomes.
  • The most striking finding is the low rate of all major morbidity and major surgical morbidity observed in both groups. When major puerperal infection was removed from the 2 composite major morbidity variables, differences in outcomes were non-significant.
  • General practitioners with a mean of 4 months’ training can perform cesarean sections with an acceptable degree of safety.

 



   POINTS DE REPÈRE DU RÉDACTEUR
 
  • Alors que certaines études sur l’obstétrique rurale donnent à croire que les issues néonatales sont équivalentes pour les césariennes pratiquées par des omnipraticiens et par des spécialistes, il y a peu de données sur les issues maternelles.
  • L’observation la plus frappante est le faible taux de morbidité majeure et de morbidité chirurgicale majeure trouvé dans les deux groupes. Si on enlève l’infection puerpérale majeure des deux variables composites de morbidité majeure, il n’y a plus de différence significative entre les issues.
  • Avec une formation de 4 mois en moyenne, les omnipraticiens sont en mesure de pratiquer des césariennes avec un degré de sécurité acceptable.

 


   Acknowledgment
TOP
 METHOD
 RESULTS
 DISCUSSION
 Footnotes
 Acknowledgment
References
 
Funding for this paper was provided by Regional Medical Associations of Hamilton and the Ontario Medical Association CME Program for Rural & Isolated Physicians.


   Footnotes
TOP
 METHOD
 RESULTS
 DISCUSSION
 Footnotes
Acknowledgment
 References
 
Contributors

Dr Aubrey-Bassler, the main author of this article, devised the concept, did the research, and wrote all drafts of the article. Dr Newbery assisted with concept and design of the study, the literature review, and writing the drafts. Dr Kelly assisted with the concept of the study, acquisition of funding, and editing drafts of the article. Dr Weaver assisted with data acquisition and analysis and read the drafts. Dr Wilson assisted with writing and editing the drafts and interpretation of data.

Competing interests

None declared

This article has been peer reviewed.

Tables 1 and 2 are available at www.cfp.ca. Go to the full text of this article on-line, then click on CFPlus in the menu at the top righthand side of the page. Back


   References
TOP
 METHOD
 RESULTS
 DISCUSSION
 Footnotes
 Acknowledgment
 References
 

  1. Iglesias S, Strachan J, Ko G, Jones LC. Advanced skills by Canada’s rural physicians. Can J Rural Med 1999;4(4):227-31.
  2. Black DP, Fyfe IM. The safety of obstetric services in small communities in northern Ontario. CMAJ 1984;130(5):571-6.[Abstract]
  3. Deutchman M, Connor P, Gobbo R, FitzSimmons R. Outcomes of cesarean sections performed by family physicians and the training they received: a 15-year retrospective study. J Am Board Fam Pract 1995;8(2):81-90.[Medline]
  4. Richards TA, Richards JL. A comparison of cesarean section morbidity in urban and rural hospitals. A three-year retrospective review of 1,177 charts. Am J Obstet Gynecol 1982;144(3):270-5.[Medline]
  5. Wen SW, Huang L, Liston R, Heaman M, Baskett T, Rusen ID, et al. Severe maternal morbidity in Canada, 1991–2001. CMAJ 2005;173(7):759-64.[Abstract/Free Full Text]
  6. Centres for Disease Control and Prevention. International classification of diseases. 9th revision: clinical modification. Atlanta, GA: Centres for Disease Control and Prevention; 2004. Available from: ftp://ftp.cdc.gov/pub/Health_Statistics/NCHS/Publications/ICD9-CM/2004. Accessed 2005 April 14.
  7. Statistics Canada. Canadian classification of diagnostic, therapeutic, and surgical procedures. Ottawa, ON: Statistics Canada; 1986.
  8. Singh V. The rural-urban income gap within provinces: an update to 2000. Rural and Small Town Canada Analysis Bulletin 2004;5(7.
  9. Larson EH, Hart LG, Rosenblatt RA. Is non-metropolitan residence a risk factor for poor birth outcome in the U.S.? Soc Sci Med 1997;45(2):171-88.[Medline]
  10. Rutter DR, Quine L. Inequalities in pregnancy outcome: a review of psychosocial and behavioural mediators. Soc Sci Med 1990;30(5):553-68.[Medline]
  11. Nesbitt TS, Connell FA, Hart LG, Rosenblatt RA. Access to obstetric care in rural areas: effect on birth outcomes. Am J Public Health 1990;80(7):814-8.[Abstract/Free Full Text]
  12. Nesbitt TS, Larson EH, Rosenblatt RA, Hart LG. Access to maternity care in rural Washington: its effect on neonatal outcomes and resource use. Am J Public Health 1997;87(1):85-90.[Abstract/Free Full Text]
  13. Larimore W, Davis A. Relation of infant mortality to the availability of maternity care in rural Florida. J Am Board Fam Pract 1996;8(5):392-9.
  14. D’Angelo L, Sokol R. Time-related peripartum determinants of postpartum morbidity. Obstet Gynecol 1980;55(3):319-23.[Medline]
  15. Sullivan SA, Smith T, Chang E, Hulsey T, VanDorsten P, Soper D. Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing postcesarean infectious morbidity: a randomized controlled trial. Am J Obstet Gynecol 2007;196:455-5, e1.[Medline]
  16. Halm EA, Lee C, Chassin MR. Is volume related to outcome in health care? A systematic review and methodologic critique of the literature. Ann Intern Med 2002;137(6):511-20.[Abstract/Free Full Text]
  17. Heller G, Richardson DK, Schnell R, Misselwitz B, Kunzel W, Schmidt S. Are we regionalized enough? Early-neonatal deaths in low-risk births by the size of delivery units in Hesse, Germany 1990–1999. Int J Epidemiol 2002;31(5):1061-8.[Abstract/Free Full Text]
  18. Heaphy PE, Bernard SL. Maternal complications of normal deliveries: variation among rural hospitals. J Rural Health 2000;16(2):139-47.[Medline]
  19. Kriebel SH, Pitts JD. Obstetric outcomes in a rural family practice: an eight-year experience. J Fam Pract 1988;27(4):377-84.[Medline]
  20. Klein MC, Spence A, Kaczorowski J, Kelly A, Grzybowski S. Does delivery volume of family physicians predict maternal and newborn outcome? CMAJ 2002;166(10):1257-63.[Abstract/Free Full Text]
  21. Hawker GA, Coyte PC, Wright JG, Paul JE, Bombardier C. Accuracy of administrative data for assessing outcomes after knee replacement surgery. J Clin Epidemiol 1997;50(3):265-73.[Medline]
  22. Humphries KH, Rankin JM, Carere RG, Buller CE, Kiely FM, Spinelli JJ. Comorbidity data in outcomes research: are clinical data derived from administrative databases a reliable alternative to chart review? J Clin Epidemiol 2000;53(4):343-9.[Medline]
  23. Lee D, Donovan L, Austin P, Gong Y, Liu P, Rouleau J, et al. Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research. Med Care 2005;43(2):182-8.[Medline]
  24. Levy AR, Tamblyn RM, Fitchett D, McLeod PJ, Hanley JA. Coding accuracy of hospital discharge data for elderly survivors of myocardial infarction. Can J Cardiol 1999;15(11):1277-82.[Medline]
  25. Seidman DS, Paz I, Nadu A, Dollberg S, Stevenson DK, Gale R, et al. Are multiple cesarean sections safe? Eur J Obstet Gynecol Reprod Biol 1994;57(1):7-12.[Medline]
  26. Klein M, Johnston S, Christilaw J, Carty E. Mothers, babies, and communities. Centralizing maternity care exposes mothers and babies to complications and endangers community sustainability. Can Fam Physician 2002;48(7):1177-9. (Eng), 1183–5 (Fr).[Free Full Text]



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