The following are among the criteria for diagnosing EoE:
Symptoms related to esophageal dysfunction Eosinophil-predominant inflammation on esophageal biopsy, characteristically consisting of a peak value of ≥ 15 eosinophils per high-powered field Mucosal eosinophilia is isolated to the esophagus and persists after a PPI trial Secondary causes of esophageal eosinophilia have been excluded
-eosinophilic gastrointestinal diseases (eg, eosinophilic gastritis, colitis) -PPI-responsive esophageal eosinophilia -celiac disease, Crohn disease -hypereosinophilic syndrome
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