RT Journal Article
SR Electronic
T1 Antiepileptic drugs in pregnancy and hemorrhagic disease of the newborn
JF Canadian Family Physician
JO Can Fam Physician
FD The College of Family Physicians of Canada
SP 1291
OP 1292
VO 56
IS 12
A1 Aleksey Kazmin
A1 Renee C. Wong
A1 Mathew Sermer
A1 Gideon Koren
YR 2010
UL http://www.cfp.ca/content/56/12/1291.abstract
AB QUESTION What is the current evidence regarding the association between hemorrhagic disease of the newborn and maternal use of hepatic enzyme-inducing antiepileptic drugs (eg, carbamazepine, phenobarbitone, topiramate)? ANSWER Women with epilepsy who take enzyme-inducing antiepileptic drugs should be advised that there is no adequate evidence to support or refute taking vitamin K in late pregnancy to prevent bleeding complications in a newborn.