PT - JOURNAL ARTICLE AU - Ruth Law AU - Caroline Maltepe AU - Pina Bozzo AU - Adrienne Einarson TI - Treatment of heartburn and acid reflux associated with nausea and vomiting during pregnancy DP - 2010 Feb 01 TA - Canadian Family Physician PG - 143--144 VI - 56 IP - 2 4099 - http://www.cfp.ca/content/56/2/143.short 4100 - http://www.cfp.ca/content/56/2/143.full SO - Can Fam Physician2010 Feb 01; 56 AB - QUESTION In addition to suffering from nausea and vomiting of pregnancy, which is being treated with antiemetics, some of my pregnant patients complain of heartburn and acid reflux. Should these symptoms also be treated and, if so, which acid-reducing medications are safe for use during pregnancy? ANSWER Increased severity of nausea and vomiting of pregnancy is associated with the presence of heartburn and acid reflux. Antacids, histamine-2 receptor antagonists, and proton pump inhibitors can be used safely during pregnancy, as large studies have been published with no evidence of adverse fetal effects.