RT Journal Article SR Electronic T1 Human papillomavirus vaccine and pregnancy JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 268 OP 269 VO 58 IS 3 A1 Andrea Narducci A1 Adrienne Einarson A1 Pina Bozzo YR 2012 UL http://www.cfp.ca/content/58/3/268.abstract AB Question A patient of mine who recently learned she was 6 weeks pregnant had received the recombinant human papillomavirus (HPV) quadrivalent vaccine at 4 weeks of gestation. She is quite worried about how this will affect her baby. What is known about the safety of the HPV vaccine during pregnancy? Answer The HPV vaccine is generally not recommended for use in pregnant women. However, theoretically, because it is not a live vaccine, it is not expected to be associated with an increased risk. Also, information from the manufacturer’s pregnancy registry and phase 3 clinical trials does not indicate an increased risk of fetal malformations or other adverse effects due to the vaccine.