TY - JOUR T1 - Acetaminophen in children JF - Canadian Family Physician JO - Can Fam Physician SP - 1065 LP - 1066 VL - 59 IS - 10 AU - Ran D. Goldman Y1 - 2013/10/01 UR - http://www.cfp.ca/content/59/10/1065.abstract N2 - Question I frequently suggest to parents to use acetaminophen to treat their children’s fever and pain. Recently, I had a child in my office who presented with a target-lesion skin rash a day after receiving acetaminophen. The rash resolved after 3 days and after stopping administration of acetaminophen. Does acetaminophen carry a risk of adverse events such as this? Answer Like any other medication or active substance, acetaminophen preparations might carry a risk of adverse events. In recent years a potential association between acetaminophen and asthma was investigated, and the US Food and Drug Administration recently published a warning about potential severe but rare skin reactions associated with acetaminophen. Although acetaminophen is mostly a safe medication, health care providers should be alert and advise parents about the possibility of rare but severe adverse events. ER -