RT Journal Article SR Electronic T1 Botulinum toxin type A in pregnancy JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 1183 OP 1184 VO 59 IS 11 A1 Michael Tan A1 Eunji Kim A1 Gideon Koren A1 Pina Bozzo YR 2013 UL http://www.cfp.ca/content/59/11/1183.abstract AB Question My patient received 62 units of botulinum toxin type A (BTX-A) for facial lines. Two weeks later, she found out that she was pregnant. Will this cause any harm to her fetus? Answer Botulinum toxin is not expected to be present in systemic circulation following proper intramuscular or intradermal injection. Moreover, BTX-A, which has a high molecular weight, does not appear to cross the placenta. From the 38 pregnancies reported in the literature, including women who had botulism poisoning during pregnancy, exposure to BTX-A does not appear to increase the risk of adverse outcome in the fetus.