RT Journal Article SR Electronic T1 Optimizing medications in older adults with cognitive impairment JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 646 OP 652 VO 64 IS 9 A1 Linda Lee A1 Tejal Patel A1 Frank Molnar A1 Dallas Seitz YR 2018 UL http://www.cfp.ca/content/64/9/646.abstract AB Objective To provide primary care physicians with an approach to medication optimization in older adults with cognitive impairment.Sources of information The approach is based on an accredited memory clinic training program developed by the Centre for Family Medicine Primary Care Collaborative Memory Clinic.Main message Dementia increases the risk of medication-related adverse events and adds to the complexity and challenge of providing optimal care for these older adults. Considerations include medication adherence, appropriate therapeutic targets for comorbid conditions, minimized use of medications with potentially adverse cognitive effects, and rational use and monitoring of cognition-enhancing drugs. Medication management plans must be individualized and based on goals of care.Conclusion Primary care physicians must consider many factors in optimizing medications for those with cognitive impairment.