RT Journal Article SR Electronic T1 Top studies relevant to primary care from 2018 JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 260 OP 263 VO 65 IS 4 A1 Danielle Perry A1 Samantha Moe A1 Christina Korownyk A1 Adrienne J. Lindblad A1 Michael R. Kolber A1 Betsy Thomas A1 Joey Ton A1 Scott Garrison A1 G. Michael Allan YR 2019 UL http://www.cfp.ca/content/65/4/260.abstract AB Objective To summarize high-quality studies for 10 topics from 2018 that have strong relevance to primary care practice.Quality of evidence Study selection involved routine literature surveillance by a group of primary care health professionals. This included screening abstracts of important journals and Evidence Alerts, as well as searching ACP Journal Club.Main message Topics of the 2018 articles include whether low-dose acetylsalicylic acid improves health outcomes like cardiovascular disease (CVD); whether a low-carbohydrate diet is better than a low-fat diet for weight loss (and whether genetics matter); whether vaginal estradiol is superior to placebo for vulvovaginal symptoms of menopause; whether opioid management is better than nonopioid management for chronic back or osteoarthritis pain; whether additional water intake will decrease recurrent urinary tract infections; whether omega-3 fatty acids prevent CVD or reduce dry eyes; whether the new drug icosapent improves CVD; whether bath additives help eczema; whether acetaminophen can prevent recurrent febrile seizures; and recommendations for glycemic targets in diabetes based on reviews of evidence and other guidelines. Five “runner-up” studies are also briefly reviewed.Conclusion Research from 2018 produced several high-quality studies in CVD but also spanned the breadth of primary care including pediatrics, women’s health, and pain management, among other areas.