Summary of evidence on associations between consumption of dietary fibre and risk of CRC: Studies are level II evidence.
| STUDY | DETAILS OF STUDY | RESULTS |
|---|---|---|
| Terry et al,16 2001 | Prospective cohort study of 61 463 women | Very low consumption of fruit and vegetables raises risk of CRC |
| Asano and McLeod,17 2002 | Meta-analysis (5 randomized controlled trials) | Increase in dietary fibre intake does not reduce incidence or recurrence of adenomatous polyps |
| Levi et al,18 2001 | Case-control study: 286 cases of CRC compared with 550 controls | Vegetable fibre appears to be more protective against CRC than either fruit or grain fibre |
| Bingham et al,19 2003 | Prospective cohort study of 19 978 patients | Intake of fibre was inversely related to incidence of large-bowel cancer |
| Mai et al,20 2003 | Prospective cohort study | No association between fibre intake and CRC |
| Peters et al,21 2003 | Cancer screening trial | High dietary fibre lowers risk of adenomas |
CRC—colorectal cancer