Projected outcomes from universal screening and risk-based maternal GBS prophylaxis in Winnipeg, Man, region: N = 100 000.
| RISK STATUS | UNIVERSAL SCREENING N (%) | RISK-BASED PROPHYLAXIS N (%) |
|---|---|---|
| Positive GBS carriers | 26 100 (26.1) | 26 100 (26.1) |
| Symptomatic carriers | 7726 (7.7) | 7726 (7.7) |
| Asymptomatic carriers | 18 374 (18.4) | 18 374 (18.4) |
| Women receiving prophylactic antibiotics* | 26 100 (26.1) | 7726 (7.7) |
| Neonatal GBS infection† | 3 (0.003) | 32 (0.032) |
| Neonatal GBS deaths† | 0.15 (0.00015) | 1.6 (0.0016) |
GBS—group B streptococcus.
↵* Does not include GBS culture–negative women presenting with risk factors for GBS transmission receiving prophylactic antibiotics.
↵† Does not include neonatal GBS infections arising from GBS culture–positive women with risk factors for neonatal GBS transmission, nor those arising from GBS culture negative women (equivalent in both groups).