REACTION TYPE | PRESENT ATION | DIFFERENTIAL DIAGNOSES TO CONSIDER |
---|---|---|
igE mediated | ||
Respiratory | Rhinoconjunctivitis
Asthma (wheeze, cough) Laryngeal edema Otitis media with effusion | Primary respiratory problem |
Cutaneous | Atopic dermatitis
Urticaria Angioedema | Food allergy
Environmental allergy Primary atopy |
Gastrointestinal | Oral allergy syndrome
Nausea and vomiting Colic Diarrhea | Food or environmental allergy
Infection, delayed gastric emptying, malrotation, celiac disease (younger than 6 mo), cystic fibrosis |
Non–Ige mediated | ||
Respiratory | Pulmonary hemosiderosis (Heiner syndrome) | None |
Cutaneous | Contact rash
Atopic dermatitis | Food or environmental allergy
Primary atopy |
Gastrointestinal | Gastroesophageal reflux
Transient enteropathy Protein-losing enteropathy Enterocolitis syndrome Colitis Constipation Failure to thrive | Physiologic reflux, delayed
gastric emptying, celiac disease (younger than 6 mo), cystic fibrosis Anal fissure Hypercalcemia, Hirschsprung disease, hypothyroidism, functional gastrointestinal disorders |
Other | ||
Unclassified (rare) | Anemia (without colitis)
Arthritis Henoch-Schönlein purpura Migraine | Broad |