Table 1

Clinical characteristics of 9 cases of PBC associated with PA reported in the literature: All patients were female.

STUDY	AGE, Y	PRIMARY SYMPTOM	TIME LAPSED BETWEEN ONSET OF EACH CONDITION	AST/ALT, IU/L	ALP/GGT, IU/L	T/DBIL, mg/dL	Hb, g/dL	MCV, fL	VITAMIN B12, pg/mL
Renoux et al,2 1980	68	Pruritus	Simultaneous	NR/22	Elevated/NR	2.6/NR	8.1	NR	70
Renoux et al,2 1980	46	Pruritus	10 y	NR/26	Elevated/NR	2.4/NR	NR	NR	NR
Renoux et al,2 1980	66	Pruritus	13 y	NR/32	Elevated/NR	3.5/NR	11.0	NR	NR
Renoux et al,2 1980	72	Pruritus	Simultaneous	NR/12	Elevated/NR	1.8/NR	9.6	NR	134
Arikan et al,3 1994	54	Pruritus	5 mo	141/84	850/88	5.0/2.8	11.8	98.0	100
Dohmen et al,4 1999	72	Dyspnea	Simultaneous	26/13	711/317	1.4/0.3	7.3	132.5	130
Takahashi et al,5 2001	52	Asymptomatic	16 y	51/57	737/434	1.1/1.0	7.1	NR	99
Aoyama et al,6 2002	59	Asymptomatic	5 y	Abnormal value/NR	NR/NR	4.0/2.0	6.4	136.0	85
Chung et al,7 2010	46	Fatigue	Simultaneous	157/169	2063/169	12.4/7.9	10.5	114.8	119

ALP—alkaline phosphatase, ALT—alanine aminotransferase, AST—aspartate aminotransferase, GGT—γ-glutamyl transpeptidase, Hb—hemoglobin, MCV—mean corpuscular volume, NR—not reported, PA—pernicious anemia, PBC—primary biliary cirrhosis, T/DBIL—total and direct bilirubin.