Table 1

Drugs associated with erectile dysfunction

TYPE OF DRUGEXAMPLES
Acid suppressionranitidine, cimetidine
Anticonvulsantscarbamazepine, gabapentin, phenytoin, phenobarbital, pregabalin,11 topiramate
AntidepressantsSSRIs, TCAs, lithium, MAOIs
Antipsychoticshaloperidol, phenothiazines
AntihypertensivesBBs, methyldopa, clonidine; CCBs (less likely)
Cardiac-relateddigoxin, fibrates, statins
Diureticsspironolactone, thiazides (especially higher doses than are now used for hypertension, eg, hydrochlorothiazide ≥ 50 mg)
Hormonalprogesterone, estrogen, corticosteroids, 5α-reductase inhibitors, cyproterone acetate
Immunomodulatorsinterferon α
NSAIDsindomethacin12
  • BB—β-blocker, CCB—calcium channel blocker, MAOI—monoamine oxidase inhibitor, NSAID—nonsteroidal anti-inflammatory drug, SSRI—selective serotonin reuptake inhibitor, TCA—tricyclic antidepressant. Data from Katz and Katz,9 McVary,10 Hitiris et al,11 and Miller et al.12