Table 1.

Complementary and alternative medicine therapies for the common cold

INTERVENTIONEVIDENCE FOR PREVENTION (LEVEL*)EVIDENCE FOR TREATMENT (LEVEL*)
Echinacea purpureaNo evidence found in 2 RCTs (level IIa)8,9Evidence found in 5 of 6 RCTs (level IIa)1015
Zinc lozengesNo trials evaluate preventionEvidence found in 5 of 9 RCTs (level IIa)1624
Vitamin CEvidence found in meta-analysis of 30 RCTs; more benefit in children and in adults under stress (level I)25No evidence found in meta-analysis of 11 RCTs (level I)25
GinsengInconsistent; evidence found in 2 of 4 RCTs (level IIb)2629No trials evaluate treatment
Garlic (allicin)Evidence found in 1 RCT (level IIb)30No trials evaluate treatment
ProbioticsNo evidence found in 4 of 6 RCTs (level IIa)3136No trials evaluate treatment
  • RCT—randomized controlled trial.

  • * Levels of evidence indicated are taken from the Oxford Centre for Evidence-Based Medicine.37