Health functioning, impairment, and work loss among participants who did or did not screen positive for lifetime bipolar disorder symptoms: A) Health functioning and work loss; B) impairment.
| A) | ||||
| MEASURE | PARTICIPANTS WHO SCREENED POSITIVE (N = 364) MEAN (SD) | PARTICIPANTS WHO SCREENED NEGATIVE (N = 940) MEAN (SD) | UNADJUSTED P VALUE* | ADJUSTED CHANGE SCORE (95% CI)† |
| Health functioning‡ | ||||
| • SF-12 mental health component score | 31.41 (10.42) | 36.37 (11.87) | < .001 | −4.48 (−5.89 to −3.07) |
| • SF-12 physical health component score | 43.90 (11.88) | 47.84 (11.72) | < .001 | −4.08 (−5.49 to −2.67) |
| Work loss§ | ||||
| • Days lost in the past week | 1.60 (2.37) | 1.09 (2.03) | < .001 | 0.41 (0.14 to 0.68) |
| • Days underproductive in the past week | 2.92 (2.51) | 1.88 (2.53) | < .001 | 0.95 (0.66 to 1.24) |
| B) | ||||
| MEASURE | SCREENED POSITIVE (N = 364) N (%) | SCREENED NEGATIVE (N = 940) N (%) | UNADJUSTED P VALUE* | ADJUSTED RELATIVE RISK (95% CI)† |
| Impairment|| | ||||
| • Work or school | 247 (67.86) | 392 (41.70) | < .001 | 1.64 (1.50 to 1.77) |
| • Social | 245 (67.31) | 308 (32.77) | < .001 | 2.08 (1.89 to 2.24) |
| • Family life or home responsibilities | 238 (65.38) | 310 (32.98) | < .001 | 2.00 (1.82 to 2.18) |
SF-12—12-Item Short-Form Health Survey.
↵* Unadjusted t test for continuous variables or χ2 test for binomial variables.
↵† Analysis of covariance adjusting for age, sex, and education.
↵‡ SF-12 health-related quality of life.
↵§ Days lost or underproductive in the past week related to the disorder.
↵|| Impairment defined as a subscale score of ≥ 7 (marked or extreme impairment) on the work, social, and family life subscales of the Sheehan Disability Scale. For the work subscale, data from participants who had not worked or studied at all during the past week for reasons unrelated to the disorder were excluded.