Table 1

Grades of recommendations and levels of evidence from the Canadian Task Force on Preventive Health Care

GRADE OR LEVELRECOMMENDATION OR EVIDENCE
AThere is good evidence to recommend the clinical preventive action
BThere is fair evidence to recommend the clinical preventive action
CThe existing evidence is conflicting and does not allow a recommendation for or against the use of the clinical preventive action; however, other factors might influence decision making
DThere is fair evidence to recommend against the clinical preventive action
EThere is good evidence to recommend against the clinical preventive action
FThere is insufficient evidence (in quantity or quality) to make a recommendation; however, other factors might influence decision making
IAt least 1 properly conducted randomized controlled trial, systematic review, or meta-analysis
IIOther comparison trials, non-randomized studies, cohort studies, case-control studies, or epidemiologic studies, and preferably more than 1 study
IIIExpert opinion or consensus statements
  • Adapted from the Canadian Task Force on Preventive Health Care.1