Risk of CD in patients with low BMD compared with control groups evaluated by the same screening algorithms
| AUTHOR, YEAR, COUNTRY | CHARACTERISTICS OF PATIENTS WITH LOW BMD | CHARACTERISTICS OF CONTROL GROUP | CD PREVALENCE IN PATIENTS WITH LOW BMD, % (CASES/N) | CD PREVALENCE IN CONTROL GROUP, % (CASES/N) | P VALUE |
|---|---|---|---|---|---|
| Drummond et al,52 2003, Ireland | 366 women (82% postmenopausal) attending a bone densitometry unit Mean age 56 y (range 28–96 y) T-score ≤ −1.0 | 89 women (45% postmenopausal) attending the same bone densitometry unit T-score > −1.0 | 2.2 (8/366) | 0 (0/89) | .364 |
| González et al,53 2002, Argentina | 127 postmenopausal women Mean age 68 y (range 50–82 y) T-score < −2.5 | 747 women, mean age 29 y (range 16–79 y) attending an obligatory prenuptial examination in the same geographic area | 0.8 (1/127) | 0.8 (6/747) | > .99 |
| Sanders et al,572005, United Kingdom | 674 individuals (95% women) referred for DEXA scan from primary or secondary care Mean age 53 y (range 21–69 y) Total group: T-score ≤ −1.0 | 304 individuals of the same population T-score > −1.0 | 1.5 (10/674) | 0.7 (2/304) | .360 |
| Osteopenia: T-score −2.5 ≤ −1.0 | 1.2 (5/431) | 0.7 (2/304) | .7058 | ||
| Osteoporosis: T-score ≤ −2.5 | 2.1 (5/243) | 0.7 (2/304) | .2505 | ||
| Stenson et al,582005, United States | 266 individuals (90% female, most postmenopausal) attending a university bone clinic Mean age 57 y T-score ≤ −2.5 | 574 individuals (90% female, most postmenopausal) attending the same clinic Mean age 63.2 y T-score > −2.5 | 3.4 (9/266) | 0.2 (1/574) | < .001 |
BMD—bone mineral density, CD—celiac disease, DEXA—dual-energy x-ray absorptiometry.