Table 2.

Treatment groups likely to benefit from statin therapy

TREATMENT GROUP	RECOMMENDATIONS
Secondary prevention for those aged ≤ 75 y with CVD	High-dose statin therapy or maximally tolerated statin dose
Primary prevention for those aged ≥ 21 y with LDL cholesterol > 5.0 mmol/L	High-dose statin therapy or maximally tolerated statin dose Look for secondary cause or family history
Primary prevention for patients with diabetes aged 40 to 75 y with LDL cholesterol levels between 2.0 and 5.0 mmol/L	If no risk factors are present, use moderate-intensity statins If risk factors are present or 10-y CVD risk is ≥ 7.5%, use high-intensity statins or maximally tolerated statin dose
Primary prevention for those aged 40 to 75 y with no CVD or diabetes who have LDL cholesterol levels between 2.0 and 5.0 mmol/L	With 10-y CVD risk of ≥ 7.5%, moderate- or high-intensity statin depending on level of risk