Results from each unique search query and the 5 algorithms with the best test characteristics (based on the youden index)
| SEARCH STRATEGY | RESULTS | SENSITIVITY, % (95% CI) | SPECIFICITY, % (95% CI) | YOUDEN INDEX* | |||
|---|---|---|---|---|---|---|---|
| TP | FP | FN | TN | ||||
| Individual search queries | |||||||
| 1. Asthma in disease registry | 8 | 4 | 104 | 282 | 7.1 (4.6 to 9.7) | 98.6 (97.4 to 99.8) | 0.057 |
| 2. Billing diagnostic code 493 | 88 | 31 | 24 | 255 | 78.6 (74.5 to 82.6) | 89.2 (86.1 to 92.2) | 0.677 |
| 3. Asthma in CPP | 71 | 22 | 41 | 264 | 63.4 (58.7 to 68.1) | 92.3 (89.7 to 94.9) | 0.557 |
| 4. Asthma medications | 88 | 104 | 24 | 182 | 78.6 (74.5 to 82.6) | 63.6 (58.9 to 68.4) | 0.422 |
| 5. Asthma in chart notes | 95 | 69 | 17 | 217 | 84.8 (81.3 to 88.3) | 75.9 (71.7 to 80.1) | 0.607 |
| Search algorithms | |||||||
| 6. Asthma in CPP OR billing diagnostic code 493 | 101 | 46 | 11 | 240 | 90.2 (87.3 to 93.1) | 83.9 (80.3 to 87.5) | 0.741 |
| 7. Asthma in CPP OR billing diagnostic code 493 (with exclusion of diagnostic codes 491, 492, and 496) | 97 | 42 | 15 | 244 | 86.6 (83.3 to 90.0) | 85.3 (81.8 to 88.8) | 0.719 |
| 8. (Asthma in chart notes OR asthma medications) AND billing diagnostic code 493 | 87 | 23 | 25 | 263 | 77.7 (73.6 to 81.8) | 92.0 (89.3 to 94.6) | 0.696 |
| 9. (Billing diagnostic code 493 OR asthma medications) AND asthma in chart notes | 94 | 46 | 18 | 240 | 83.9 (80.3 to 87.5) | 83.9 (80.3 to 87.5) | 0.678 |
| 10. Billing diagnostic code 493 AND asthma in chart notes | 83 | 20 | 29 | 266 | 74.1 (69.8 to 78.4) | 93.0 (90.5 to 95.5) | 0.671 |
CPP—cumulative patient profile, FN—false negative, FP—false positive, TN—true negative, TP—true positive.
↵* J = sensitivity + specificity - 1.