Diagnostic accuracy of frailty markers
| FRAILTY-DEFINING CRITERION | SENSITIVITY, % (95% CI) | SPECIFICITY, % (95% CI) | POSITIVE PREDICTIVE VALUE, % (95% CI) | ACCURACY, % (95% CI) | POSITIVE LIKELIHOOD RATIO (95% CI) |
|---|---|---|---|---|---|
| Individual markers | |||||
| • Gait speed | 87.5 (66.5–96.7) | 94.6 (91.6–96.7) | 52.5 (36.3–68.1) | 94.2 (91.2–96.3) | 16.2 (10.3–26.0) |
| • Grip strength | 100.0 (83.4–100.0) | 90.5 (86.9–93.2) | 42.4 (29.8–55.9) | 91.1 (87.7–93.6) | 10.5 (7.6–14.5) |
| • Low exercise | 100.0 (83.4–100.0) | 86.0 (81.9–89.3) | 33.3 (23.1–45.2) | 86.9 (83.0–90.0) | 7.1 (5.5–9.2) |
| • Weight loss | 8.3 (0.4–40.2) | 97.4 (94.4–98.8) | 12.5 (0.7–53.3) | 93.5 (90.0–96.0) | 3.2 (0.4–23.6) |
| • Exhaustion | 81.8 (47.8–96.8) | 90.4 (85.2–94.0) | 32.1 (16.6–52.4) | 90.0 (84.9–93.5) | 8.5 (5.1–14.2) |
| Combined markers | |||||
| • Gait speed and grip strength | 87.5 (66.5–96.7) | 99.2 (97.3–99.8) | 87.5 (66.5–96.7) | 98.4 (96.4–99.4) | 103.5 (33.2–322.7) |