Final multivariable model for a new antidepressant prescription for patients without depression diagnosis: Among the 3252 patients without depression diagnosis, 276 (8.5%) were given a new antidepressant prescription.
| CHARACTERISTIC | NEW ANTIDEPRESSANT PRESCRIPTION | ||
|---|---|---|---|
| ESTIMATED OR | 95% CI | P VALUE | |
| Male sex | 0.77 | 0.59–1.01 | .056 |
| Age, per 5-y increase* | 0.86 | 0.78–0.94 | .001 |
| Anti-dementia medication prescription† | 1.57 | 1.16–2.12 | .003 |
| Polypharmacy‡ | 1.29 | 0.92–1.64 | .058 |
| Polypharmacy interaction with age increase§ | 1.21 | 1.01–1.46 | .037 |
OR—odds ratio.
↵* This OR would be valid for people with no polypharmacy.
↵† Prescription for anti-dementia medication on date of dementia diagnosis.
↵‡ At least 5 different prescriptions filled within a 30-day window, within 6 months of dementia diagnosis. This OR estimate valid for those aged 82.
↵§ Change in OR for people with polypharmacy for each 5-year increase in age.