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Health-related quality of life deficits associated with diabetes and comorbidities in a Canadian National Population Health Survey

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Abstract

Objective: To assess the impact of comorbid heart disease, stroke and arthritis on health-related quality of life (HRQL) in people with diabetes in the general Canadian population. Methods: Data were collected as part of the 1996–1997 Canadian National Population Health Survey. HRQL was assessed using overall Health Utilities Index Mark 3 (HUI3) and single attribute utility scores. Respondents (N=66,093) were classified into 1 of 16 groups based on the presence or absence of diabetes, heart disease, stroke, and arthritis, in all possible combinations and HRQL scores were compared using analysis of covariance. Results: Overall HUI3 scores for respondents with diabetes alone (0.88, 95 CI: 0.87–0.89) were lower than controls (0.92 95 CI: 0.92–0.92, p < 0.001). Overall HUI3 scores for diabetes in combination with␣heart disease (0.77, 95 CI: 0.74–0.79), arthritis (0.78, 95 CI: 0.77–0.79) or stroke (0.79, 95 CI: 0.74–0.85) were considerably lower than diabetes alone. Triplets of comorbidities were associated with overall HRQL deficits of approximately 0.26–0.30, relative to controls. Conclusions: The illness burden experienced by individuals with diabetes is not only associated with diabetes itself, but largely with comorbid medical conditions.

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Abbreviations

ANCOVA -:

Analysis of Covariance

BMI -:

Body Mass Index

HRQL -:

Health Related Quality of Life

HUI3 -:

Health Utilities Index Mark 3

NPHS -:

National Population Health Survey

95 CI:

95 Confidence Interval

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Correspondence to Jeffrey A. Johnson.

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Maddigan, S.L., Feeny, D.H. & Johnson, J.A. Health-related quality of life deficits associated with diabetes and comorbidities in a Canadian National Population Health Survey. Qual Life Res 14, 1311–1320 (2005). https://doi.org/10.1007/s11136-004-6640-4

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