Arthropathy induced by antibacterial fused N-alkyl-4-pyridone-3-carboxylic acids
References (1)
- et al.
Nalidixic acid arthralgia
Can. Med. Ass. J.
(1972)
Cited by (143)
Sulfonamides, quinolones, antiseptics, and disinfectants
2023, Medicinal Chemistry of Chemotherapeutic Agents: a Comprehensive Resource of Anti-infective and Anti-cancer DrugsAcute Kidney Injury in Pregnancy: The Changing Landscape for the 21st Century
2018, Kidney International ReportsCitation Excerpt :Treatment of pyelonephritis, on the other hand, requires the use of parenteral antibiotics (Table 2). We recommend avoidance of fluoroquinolones and aminoglycosides if possible, given concerns over animal reports of arthropathy of the fetus in the former class85 and the risk of nephrotoxicity of the mother in the latter. Successful treatment should be confirmed with a negative urine culture 1 to 2 weeks after completion of antibiotics to demonstrate “test of cure.”
Acute Kidney Injury in Pregnancy
2017, Seminars in NephrologyBones, Joints, and Synovia
2017, Boorman's Pathology of the Rat: Reference and AtlasCutaneous infectious diseases: Kids are not just little people
2015, Clinics in DermatologyCitation Excerpt :Antimicrobials are one of the most commonly used medications in the pediatric population; however, two broad categories of antimicrobials historically have been contraindicated in this age group: fluoroquinolones and tetracyclines.42 Fluoroquinolones are an important class of antimicrobials, given their broad spectrum of activity (including gram-negative, gram-positive, and atypical organisms), good tissue penetration, and oral bioavailability42,43; however, their use in children is generally discouraged ,given the arthropathy seen in juvenile animals in experimental trials.44 Preclinical studies of quinolones in juvenile beagle dogs revealed articular cartilage damage in weight-bearing joints.45–47
Bone and Joints
2013, Haschek and Rousseaux's Handbook of Toxicologic Pathology