Relationship of low-dose aspirin to Gl injury and occult bleeding: A pilot study†
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Cited by (22)
Tests and investigations for colorectal cancer screening
2014, Clinical BiochemistryCitation Excerpt :A meta-analysis [92] and more recently a systematic review [93] support decisions made in the England (and elsewhere) not to impose dietary restrictions as part of the gFOBt screening process. The test positivity of gFOBt may also be affected in individuals with an increased likelihood of bleeding (e.g. those taking drugs such as warfarin or aspirin) [94,95], although some evidence suggests otherwise [96–98]. Current advice is that withdrawal of NSAIDs and anticoagulant drugs before participating in CRC screening using gFOBt is not necessary [98].
Gastrointestinal malignancies and cardiovascular diseases-Non-negligible comorbidity in an era of multi-antithrombotic drug use
2011, Journal of CardiologyCitation Excerpt :Several clinical studies, although not large-scale, have been designed to answer this question. In a double-blind, prospective study, Greenberg et al. reported that, in the absence of frank ulceration, low-dose aspirin did not result in a positive FOBT [29]. In that study, however, healthy volunteers underwent only 30 days of treatment with daily aspirin or placebo.
Performance improvements of stool-based screening tests
2010, Best Practice and Research: Clinical GastroenterologyCitation Excerpt :The evidence on the effect of vitamin C use on test performance was inconclusive [15]. The use of aspirin or NSAIDs does not seem to increase false-positivity of the Hemoccult II and Hemoccult II SENSA [16,17]. Thus, physicians do not need to advise participants to restrict their diet and/or medication prior to gFOBT, although usually advised otherwise by test manufacturers.
Endoscopic findings in the upper gastrointestinal tract of faecal occult blood-positive, colonoscopy-negative patients
2006, Digestive and Liver Disease
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Supported in part by an unrestricted grant from SmithKline Diagnostics; SmithKline Diagnostics supplied materials for fecal occult blood testing.