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Opioid-Induced Itching: Morphine Sulfate and Hydromorphone Hydrochloride

https://doi.org/10.1016/S0885-3924(98)00115-8Get rights and content
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Abstract

We describe a case of severe morphine-induced itch unrelieved by antihistamines, which responded to a change to hydromorphone. The possible mechanisms of opioid-induced itch are briefly discussed. It is unclear if it is due to histamine release, an opioid-receptor mediated effect, or idiosyncratic drug reaction. J. Pain Symptom Manage 1999;17:70–72.

Keywords

Opioid side effects
itch
morphine
hydromorphone
parenteral opioids

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