Feasibility and outcome of HCV treatment in a Canadian federal prison population

Am J Public Health. 2005 Oct;95(10):1737-9. doi: 10.2105/AJPH.2004.056150. Epub 2005 Aug 30.

Abstract

We assessed feasibility and outcome of hepatitis C virus (HCV) treatment in male correctional inmates in British Columbia, Canada. We reviewed the medical charts of 114 treated inmates; 80 had complete data for treatment outcome. Approximately 4 of 5 inmates completed treatment (78.8%); 66.3% achieved sustained virological response. Those who completed treatment, those with injection drug use as a risk factor, and those with genotypes 2 and 3 were significantly more likely to achieve sustained virological response. HCV treatment in correctional inmates is feasible and effective.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • British Columbia / epidemiology
  • DNA, Viral / genetics
  • Drug Combinations
  • Feasibility Studies
  • Federal Government
  • Genotype
  • Hepacivirus / classification
  • Hepacivirus / genetics
  • Hepatitis C / drug therapy*
  • Hepatitis C / epidemiology
  • Hepatitis C / etiology
  • Humans
  • Interferon-alpha / therapeutic use*
  • Male
  • Methadone / therapeutic use
  • Middle Aged
  • Multivariate Analysis
  • Narcotics / therapeutic use
  • Prevalence
  • Prisons / organization & administration*
  • Program Evaluation
  • Retrospective Studies
  • Ribavirin / therapeutic use*
  • Risk Factors
  • Substance Abuse, Intravenous / complications
  • Substance Abuse, Intravenous / drug therapy
  • Treatment Outcome

Substances

  • DNA, Viral
  • Drug Combinations
  • Interferon-alpha
  • Narcotics
  • Rebetron
  • Ribavirin
  • Methadone