Erectile dysfunction associated with pregabalin add-on treatment in patients with partial seizures: five case reports

Nikolas Hitiris; Jeannette A Barrett; Martin J Brodie

doi:10.1016/j.yebeh.2005.12.001

Erectile dysfunction associated with pregabalin add-on treatment in patients with partial seizures: five case reports

Epilepsy Behav. 2006 Mar;8(2):418-21. doi: 10.1016/j.yebeh.2005.12.001. Epub 2006 Jan 30.

Authors

Nikolas Hitiris¹, Jeannette A Barrett, Martin J Brodie

Affiliation

¹ Epilepsy Unit, Division of Cardiovascular and Medical Sciences, Western Infirmary, Glasgow, Scotland, UK.

PMID: 16446121
DOI: 10.1016/j.yebeh.2005.12.001

Abstract

Sexual dysfunction has been reported in both men and women with epilepsy. Associated factors are diverse but include, among others, antiepileptic drugs. We present the cases of 5 men who reported mild to moderate erectile dysfunction or impotence for the first time when treated with the new antiepileptic drug pregabalin as add-on therapy.

Publication types

Case Reports

MeSH terms

Adult
Anticonvulsants / adverse effects*
Anticonvulsants / therapeutic use
Drug Therapy, Combination
Epilepsies, Partial / drug therapy*
Erectile Dysfunction / chemically induced*
Humans
Male
Middle Aged
Pregabalin
Randomized Controlled Trials as Topic
gamma-Aminobutyric Acid / adverse effects
gamma-Aminobutyric Acid / analogs & derivatives*
gamma-Aminobutyric Acid / therapeutic use

Substances

Anticonvulsants
Pregabalin
gamma-Aminobutyric Acid