Late onset of a facial variant of steatocystoma multiplex - calretinin as a specific marker of the follicular companion cell layer
J Dtsch Dermatol Ges. 2008 Jun;6(6):480-2.
doi: 10.1111/j.1610-0387.2007.06603.x.
[Article in
English,
German]
Affiliation
- 1 Department of Dermatology, Clinic of Dortmund gGmbH, Beurhausstrasse, Germany. christian.riedel@klinikumdo.de
Abstract
Steatocystoma multiplex is a rare,almost exclusively autosomal dominant disease of the sebaceous glands. The sites of predilection are the sternal region, upper back, axillae and proximal parts of the extremities. A 78-year-old woman developed multiple yellowish nodules only on the face over a few months. Histology revealed large cysts with a thin wall and connection to sebaceous glands. Immunohistochemical analysis showed the inner epithelial layer of the cysts was positive with calretinin.With curettage and CO2 laser therapy, a good cosmetic result was achieved.This is the first case report in the German literature of a rare sporadic form of steatocystoma multiplex with late onset and exclusive localization in the face.
MeSH terms
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Aged
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Biomarkers / analysis
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Calbindin 2
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Facial Dermatoses / diagnosis*
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Facial Dermatoses / therapy
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Female
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Hair Follicle / metabolism*
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Hair Follicle / pathology*
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Humans
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Rare Diseases / diagnosis
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Rare Diseases / therapy
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S100 Calcium Binding Protein G / analysis*
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Sebaceous Gland Diseases / diagnosis*
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Sebaceous Gland Diseases / therapy
Substances
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Biomarkers
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CALB2 protein, human
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Calbindin 2
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S100 Calcium Binding Protein G