Resorcinol peels as a possible self-treatment of painful nodules in hidradenitis suppurativa

Clin Exp Dermatol. 2010 Jan;35(1):36-40. doi: 10.1111/j.1365-2230.2009.03377.x. Epub 2009 Jun 22.

Abstract

Background: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by abscess formation localized to apocrine sweat gland-bearing skin. The most important factor in patients' overall assessment of disease severity is pain. The duration of abscesses takes days to weeks and are always painful.

Aim: To assess the efficacy of self-treatment with topical 15% resorcinol in an open study.

Methods: The case notes of 12 women with stage 1 or 2 HS treated with topical resorcinol and followed up for at least 1 year were reviewed. The patients rated the efficacy of treatment on global maximum pain of nodules and abscesses on a visual analogue scale (VAS) and by self-report of the mean duration (days) of a painful lesion.

Results: All patients experienced a significant decrease in pain as assessed by VAS and reported a reduction in mean duration of the painful abscesses.

Conclusions: Topical treatment with 15% resorcinol reduced pain from painful nodules in all patients with HS. Further trials are warranted to confirm these results.

MeSH terms

  • Adult
  • Drug Administration Schedule
  • Female
  • Hidradenitis Suppurativa / drug therapy*
  • Hidradenitis Suppurativa / psychology
  • Humans
  • Middle Aged
  • Pain / drug therapy*
  • Pain / psychology
  • Pain Measurement
  • Patient Satisfaction
  • Quality of Life / psychology*
  • Resorcinols / administration & dosage*
  • Self Administration
  • Severity of Illness Index
  • Treatment Outcome
  • Young Adult

Substances

  • Resorcinols
  • resorcinol