Abstract
The authors determined the prevalence of certain major congenital disorders among live-born infants of 6509 mothers in a prepaid health plan for the 30-month period of January 1, 1980 through June 30, 1982 who used a wide variety of drugs during the first trimester of pregnancy. The results were similar to those obtained in this population in a prior 30-month study. No strong associations between any of the commonly used drugs and the congenital disorders studied were present.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Abnormalities, Drug-Induced / epidemiology
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Abnormalities, Drug-Induced / etiology*
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Brompheniramine / adverse effects
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Congenital Abnormalities / epidemiology*
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Congenital Abnormalities / etiology
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Dicyclomine
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Doxylamine / adverse effects
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Drug Combinations / adverse effects
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Drug-Related Side Effects and Adverse Reactions*
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Female
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Humans
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Infant, Newborn
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Phenylephrine / adverse effects
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Phenylpropanolamine / adverse effects
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Pregnancy
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Pregnancy Trimester, First*
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Pseudoephedrine
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Pyridoxine / adverse effects
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Washington
Substances
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Drug Combinations
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brompheniramine, pseudoephedrine drug combination
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dicyclomine, doxylamine, pyridoxine drug combination
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Phenylephrine
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Phenylpropanolamine
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Dicyclomine
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Pseudoephedrine
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Doxylamine
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Brompheniramine
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Pyridoxine