User profiles for D. Rolfe

Daniel J. Rolfe

- Verified email at stfc.ac.uk - Cited by 1798

Danielle Rolfe, PhD

- Verified email at uottawa.ca - Cited by 636

Cellular energy utilization and molecular origin of standard metabolic rate in mammals

DF Rolfe, GC Brown - Physiological reviews, 1997 - journals.physiology.org
The molecular origin of standard metabolic rate and thermogenesis in mammals is examined.
It is pointed out that there are important differences and distinctions between the cellular …

The causes and functions of mitochondrial proton leak

MD Brand, LF Chien, EK Ainscow, DFS Rolfe… - … et Biophysica Acta (BBA …, 1994 - Elsevier
The non-linear relationship between respiration rate and protonmotive force in isolated
mitochondria is explained entirely by Δp-dependent changes in the proton conductance of the …

The physiological significance of mitochondrial proton leak in animal cells and tissues

DFS Rolfe, MD Brand - Bioscience reports, 1997 - portlandpress.com
Mitochondrial proton leak is an important component of cellular metabolism in animals and
may account for as much as one quarter to one third of the Standard Metabolic Rate of the rat…

Contribution of mitochondrial proton leak to skeletal muscle respiration and to standard metabolic rate

DF Rolfe, MD Brand - American Journal of Physiology-Cell …, 1996 - journals.physiology.org
We have tested the hypothesis that the leak of protons across the mitochondrial inner membrane
(proton leak) is a significant contributor to standard metabolic rate (SMR). We found that …

Contribution of mitochondrial proton leak to respiration rate in working skeletal muscle and liver and to SMR

DFS Rolfe, JMB Newman… - … of Physiology-Cell …, 1999 - journals.physiology.org
Proton pumping across the mitochondrial inner membrane and proton leak back through
the natural proton conductance pathway make up a futile cycle that dissipates redox energy. …

Characteristics of mitochondrial proton leak and control of oxidative phosphorylation in the major oxygen-consuming tissues of the rat

DFS Rolfe, AJ Hulbert, MD Brand - Biochimica et Biophysica Acta (BBA) …, 1994 - Elsevier
Maintenance of an electrochemical proton gradient across the mitochondrial inner membrane
against the significant proton permeability of the membrane accounts for 25–30% of …

Cell wall constrains lateral diffusion of plant plasma-membrane proteins

…, I Lavagi, G Nageswaran, DJ Rolfe… - Proceedings of the …, 2012 - National Acad Sciences
… cytoskeletons might exert a similar influence on membrane-protein mobility in plant cells,
we incubated minimal GFP-expressing Arabidopsis seedlings with either cytochalasin D or …

[HTML][HTML] Hydrophobic fluorescent probes introduce artifacts into single molecule tracking experiments due to non-specific binding

LC Zanetti-Domingues, CJ Tynan, DJ Rolfe, DT Clarke… - PloS one, 2013 - journals.plos.org
… As a spot cannot have a value of D below zero, we conclude that these negative D values
are due to errors in D resulting mainly from localization errors, and that the maximum D error is …

[HTML][HTML] EGFR oligomerization organizes kinase-active dimers into competent signalling platforms

…, V Losasso, D Korovesis, M Hirsch, DJ Rolfe… - Nature …, 2016 - nature.com
… The average instantaneous diffusion coefficient (D) for these … curve then calculating D directly
from the gradient m of the fit, D=m/… The error in D, σ(D), is calculated from the sd of the D fits …

[HTML][HTML] Patient and public engagement in integrated knowledge translation research: are we there yet?

…, M Bains, S Carroll, DK Kandola, DE Rolfe… - Research involvement …, 2019 - Springer
Plain English summary There have been many attempts to improve how healthcare
services are developed and delivered. Despite this, we know that there are many gaps and …