Description Proton pump inhibitors (PPIs) are among the most commonly used medications
in the world. Developed for the treatment and prevention of acid-mediated upper …

Background & Aims: ANVUGIB is a common reason for hospital admission and has been
traditionally associated with a mortality rate of 5%–10%. There have been numerous …

… Specific author contributions: Targownik and Bernstein contributed equally in conceiving the
review; Targownik wrote the first draft and both Targownik and Bernstein edited and revised …

Background: The use of proton pump inhibitors has been associated with an increased risk
of hip fracture. We sought to further explore the relation between duration of exposure to …

ContextLimited evidence exists to guide the optimal frequency of repeat endoscopic
examination for colorectal cancer screening after a negative colonoscopy.ObjectiveTo determine …

… Targownik contributed to study design, data acquisition, critical revision of the manuscript
for important intellectual content, and obtained funding. Rob Deardon and Ali Rezaie …

… Targownik: analysis and interpretation of data; critical revision of the manuscript; obtained
funding. Jennifer L. Jones: analysis and interpretation of data; critical revision of the …

BACKGROUNDS & AIMS: Recent studies have shown an association between proton-pump
inhibitor use (PPI) and hip fracture. The mechanism by which PPI use promotes the …

OBJECTIVES: Previous studies have reported colectomy rates of over 50% in ulcerative
colitis (UC), although changes in management may have influenced the rates of colectomy in …

Objective The microbiome contributes to the pathogenesis of inflammatory bowel disease (IBD)
but the relative contribution of different lifestyle and environmental factors to the …