Adolescence is a time of dramatic changes in brain structure and function, and the adolescent
brain is highly susceptible to being altered by experiences like substance use. However, …

Objectives: We conducted a literature review to respond to regulatory concerns about the
quality of translated patient‐reported outcome questionnaires. Our main objective was to …

BACKGROUND: Two competing concepts address the development of involvement with
psychoactive substances: the “gateway hypothesis” (GH) and common liability to addiction (CLA…

ContextGene expression analysis has identified several breast cancer subtypes, including
basal-like, human epidermal growth factor receptor-2 positive/estrogen receptor negative (…

The Parkinson's disease (PD) substantia nigra is characterized by the presence of Lewy bodies
containing fibrillar α-synuclein. Early-onset PD has been linked to two point mutations in …

Two mutations in the gene encoding α-synuclein have been linked to early-onset Parkinson's
disease 1, 2, 3 (PD). α-Synuclein is a component of Lewy bodies, the fibrous cytoplasmic …

… For each protein, K r was calculated as the slope of a plot of log R f vs % acrylamide (Ferguson
plot). A plot of K r vs MW was used to estimate an approximate M r of 20 kDa for NACP. (C…

Cognition is 1 of 4 domains measured by the NIH Toolbox for the Assessment of Neurological
and Behavioral Function (NIH-TB), and complements modules testing motor function, …

The substantia nigra in Parkinson's disease (PD) is depleted of dopaminergic neurons and
contains fibrillar Lewy bodies comprising primarily α-synuclein. We screened a library to …

Risk factors for the newly identified “intrinsic” breast cancer subtypes (luminal A, luminal B,
basal-like and human epidermal growth factor receptor 2-positive/estrogen receptor-negative…