User profiles for M. G. Myers
Martin MyersUniversity of Michigan Verified email at umich.edu Cited by 41849 |
Mechanisms of leptin action and leptin resistance
The adipose tissue–derived hormone leptin acts via its receptor (LRb) in the brain to regulate
energy balance and neuroendocrine function. LRb signaling via STAT3 and a number of …
energy balance and neuroendocrine function. LRb signaling via STAT3 and a number of …
Measurement of blood pressure in humans: a scientific statement from the American Heart Association
…, JB Charleston, T Gaillard, S Misra, MG Myers… - …, 2019 - Am Heart Assoc
The accurate measurement of blood pressure (BP) is essential for the diagnosis and
management of hypertension. This article provides an updated American Heart Association …
management of hypertension. This article provides an updated American Heart Association …
Obesity and leptin resistance: distinguishing cause from effect
Because leptin reduces food intake and body weight, the coexistence of elevated leptin
levels with obesity is widely interpreted as evidence of ‘leptin resistance.' Indeed, obesity …
levels with obesity is widely interpreted as evidence of ‘leptin resistance.' Indeed, obesity …
Aspirin, sulfinpyrazone, or both in unstable angina: results of a Canadian multicenter trial
…, WJ Kostuk, LJ Melendez, MG Myers… - … England Journal of …, 1985 - Mass Medical Soc
We performed a randomized, double-blind, placebo-controlled trial in 555 patients with
unstable angina who were hospitalized in coronary care units. Patients received one of four …
unstable angina who were hospitalized in coronary care units. Patients received one of four …
Blood pressure measuring devices: recommendations of the European Society of Hypertension
E O'brien, B Waeber, G Parati, J Staessen, MG Myers - Bmj, 2001 - bmj.com
There is a large market for blood pressure measuring devices not only in clinical medicine
but also among the public where the demand for self measurement of blood pressure is …
but also among the public where the demand for self measurement of blood pressure is …
Phosphatidylinositol 3′‐kinase is activated by association with IRS‐1 during insulin stimulation.
JM Backer, MG Myers Jr, SE Shoelson, DJ Chin… - The EMBO …, 1992 - embopress.org
… IRS-lbac caused a small stimulation of PtdIns 3'-kinase, which may reflect the fact that IRS-lbac
contains a small amount of phosphotyrosine when isolated from Sf-9 cells (MGMyers,Jr …
contains a small amount of phosphotyrosine when isolated from Sf-9 cells (MGMyers,Jr …
STAT3 signalling is required for leptin regulation of energy balance but not reproduction
…, E Maratos-Flier, BG Neel, MW Schwartz, MG Myers Jr - Nature, 2003 - nature.com
Secretion of leptin from adipocytes communicates body energy status to the brain by
activating the leptin receptor long form (LRb). LRb regulates energy homeostasis and …
activating the leptin receptor long form (LRb). LRb regulates energy homeostasis and …
Role of IRS-2 in insulin and cytokine signalling
THE protein IRS-1 acts as an interface between signalling proteins with Src-homology-2
domains (SH2 proteins) and the receptors for insulin, IGF-1, growth hormone, several …
domains (SH2 proteins) and the receptors for insulin, IGF-1, growth hormone, several …
[PDF][PDF] Endoplasmic reticulum stress plays a central role in development of leptin resistance
… To address this question, we first pretreated the ob/ob mice with TUDCA (150 mg/kg/day) for
5 days and subsequently initiated leptin (1 mg/kg) treatment. As shown in Figure 7B, neither …
5 days and subsequently initiated leptin (1 mg/kg) treatment. As shown in Figure 7B, neither …
[HTML][HTML] Activation of downstream signals by the long form of the leptin receptor
The adipocyte-derived hormone leptin signals the status of body energy stores by activating
the long form of the leptin receptor (LRb). Activation of LRb results in the activation of the …
the long form of the leptin receptor (LRb). Activation of LRb results in the activation of the …