Perinatal exposure to maternal lamotrigine: clinical considerations for the mother and child

P Madadi, S Ito - Canadian Family Physician, 2010 - cfp.ca
QUESTION The question of neonatal safety during breastfeeding when mothers are taking
lamotrigine (LTG) has become more prevalent in my practice. There are some theoretical …

The disposition of lamotrigine throughout pregnancy

DJ Berry - Therapeutic Drug Monitoring, 1999 - journals.lww.com
Lamotrigine has been available for approximately 10 yrs. Managing epileptic patients who
become pregnant is an important issue particularly with the newer anti-epileptic drugs which …

Severe apnea in an infant exposed to lamotrigine in breast milk

E Nordmo, L Aronsen, K Wasland… - Annals of …, 2009 - journals.sagepub.com
Objective: To report a case of severe apnea in an infant exposed to lamotrigine through
breast-feeding. Case Summary: A 16-day-old infant developed several mild episodes of …

Lamotrigine in breast milk and nursing infants: determination of exposure

DJ Newport, PB Pennell, MR Calamaras… - …, 2008 - publications.aap.org
OBJECTIVE. Although lamotrigine use during pregnancy has substantially increased over
the past decade secondary to accumulated reproductive safety data, systematic data on …

Comprehensive measurements of intrauterine and postnatal exposure to lamotrigine

M Paulzen, JC Stingl, M Augustin… - Clinical …, 2019 - Springer
Objective The aim of this study was to measure and investigate correlations of lamotrigine
concentrations in maternal as well as umbilical cord blood, amniotic fluid, and breast milk to …

Evaluation of the safety of taking lamotrigine during lactation period

K Yashima, T Obara, F Matsuzaki, C Suzuki… - Breastfeeding …, 2021 - liebertpub.com
Introduction: Evaluation of the safety of taking lamotrigine (LTG) during lactation in breastfed
infants varies according to the information sources. As it is possible that prescribers may …

Lamotrigine in pregnancy and lactation: a case report

T Tomson, I Öhman, S Vitols - Epilepsia, 1997 - Wiley Online Library
Purpose: We investigated the effect of pregnancy on the kinetics of lamotrigine (LTG),
passage of LTG over the placenta and the excretion of the drug in breast milk. Methods: We …

[HTML][HTML] Monitoring of lamotrigine concentrations in mothers, colostrum, and breastfed newborns during the early postpartum period

I Kacirova, M Grundmann, H Brozmanova - Biomedicine & …, 2022 - Elsevier
Objective To analyse the concentrations of lamotrigine in maternal serum, colostrum, and
serum of breastfed newborns, and to evaluate the effect of comedication with enzyme …

Concerns regarding lamotrigine and breast-feeding

J Liporace, A Kao, A D'Abreu - Epilepsy & Behavior, 2004 - Elsevier
Purpose. Many women with epilepsy who are planning a pregnancy are treated with
lamotrigine (LTG), resulting in greater fetal exposure to the drug. Current care guidelines …

Lamotrigine in pregnancy: pharmacokinetics during delivery, in the neonate, and during lactation

I Ohman, S Vitols, T Tomson - Epilepsia, 2000 - Wiley Online Library
Purpose: To investigate the pharmacokinetics of lamotrigine (LTG) during delivery, during
the neonatal period, and lactation. Methods: High‐performance liquid chromatography was …