Bias against the null hypothesis: scaring pregnant women about drugs in pregnancy

G Koren, S Madjunkova, C Maltepe - Canadian Family Physician, 2014 - cfp.ca
Question Since the thalidomide disaster, medicine is practised as if every drug is
teratogenic, when in fact very few medications are. Pregnant women are often ready to …

Women's perception of risks of adverse fetal pregnancy outcomes: a large-scale multinational survey

I Petersen, RL McCrea, A Lupattelli, H Nordeng - BMJ open, 2015 - bmjopen.bmj.com
Objective To determine pregnant women and new mothers' perception of risks in pregnancy.
Design, settings and participants This was a large-scale multinational survey including 9113 …

Time to change our attitudes to prescribing in pregnancy

M Pownall - Women's Health Medicine, 2006 - Elsevier
This article assesses how the thalidomide disaster has caused GPs to have a difficult
approach to prescribing in pregnancy. It notes how medical opinion might look towards …

Better safe than sorry: Risk, stigma, and research during pregnancy

L Langston - Clinical research involving pregnant women, 2016 - Springer
Choosing to act within a precautionary paradigm is often the smart choice for pregnant
women and for healthcare practitioners and researchers who interact with them. However …

[HTML][HTML] Risk perception regarding drug use in pregnancy

SF Widnes, J Schjøtt - American journal of obstetrics and gynecology, 2017 - Elsevier
Pregnant women, but also physicians, have unrealistically high perceptions of teratogenic
drug effects. This may result in suboptimal treatment of disease and even influence …

Drugs in pregnancy

G Koren, A Pastuszak, S Ito - New England Journal of Medicine, 1998 - Mass Medical Soc
Before marketing a new drug, the manufacturer almost never tests the product in pregnant
women to determine its effects on the fetus. Consequently, most drugs are not labeled for …

Necessity of research for safe drug use in pregnant women

JY Han, GJ Cho, JM Oh - Journal of Korean Maternal and Child Health, 2017 - e-mch.org
The thalidomide tragedy in the 1960s has resulted in a perpetuation of a certain perception
amongst physicians and pregnant women that the use of medication during pregnancy is a …

[CITATION][C] Prescription of medications during pregnancy: accidents, compromises, and uncertainties

S Hernández‐Díaz - Pharmacoepidemiology and drug safety, 2006 - Wiley Online Library
Since the thalidomide disaster over 40 years ago, we have known that medication use in
early pregnancy poses a potential risk to the fetus. Yet, drugs typically enter the marketplace …

Drug labeling and risk perceptions of teratogenicity: a survey of pregnant Canadian women and their health professionals

M Pole, A Einarson, N Pairaudeau… - The Journal of …, 2000 - Wiley Online Library
There is a general perception that medicinal drugs are not safe in pregnancy despite the fact
that fewer than 30 drugs have been shown to cause major malformations in humans. A large …

Points to remember in prescribing drugs during pregnancy

KM Piafsky - Canadian Family Physician, 1974 - ncbi.nlm.nih.gov
Our knowledge of possible adverse drug effects on the fetus is quite limited. The doctor must
act as the fetus' first line of defence. Mothers must be educated about the dangers of self …