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Research ArticleClinical Review

Not enough vitamin D

Health consequences for Canadians

Gerry Schwalfenberg
Canadian Family Physician May 2007; 53 (5) 841-854;
Gerry Schwalfenberg
Clinical lecturer in the Department of Family Medicine at the University of Alberta in Edmonton
MD CCFP
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Abstract

OBJECTIVE To review the evidence on vitamin D (VTD) insufficiency and deficiency from a Canadian perspective and to highlight some of the known and evolving implications of insufficiency or deficiency for health.

QUALITY OF EVIDENCE PubMed was searched for articles on VTD insufficiency or deficiency and the role they play in various diseases and conditions. Level I and II evidence indicates that lack of VTD has a major role in short- and long-latency diseases.

MAIN MESSAGE The long winters in Canada and lack of exposure to the sun contribute to lower levels of VTD among Canadians in late winter and spring. Currently recommended levels of fortification and supplementation are likely not high enough to restore adequate levels of VTD in the body. Repletion and maintenance therapy might be needed.

CONCLUSION Many Canadians are at risk of VTD insufficiency or deficiency. Assessment of VTD status is important because optimal levels of VTD have been determined for various conditions. Low levels of VTD have negative implications for bone health and the health of other cell types.

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Canadian Family Physician: 53 (5)
Canadian Family Physician
Vol. 53, Issue 5
1 May 2007
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Not enough vitamin D
Gerry Schwalfenberg
Canadian Family Physician May 2007, 53 (5) 841-854;

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Gerry Schwalfenberg
Canadian Family Physician May 2007, 53 (5) 841-854;
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  • Article
    • Abstract
    • Quality of evidence
    • Background
    • Assessing VTD status
    • Prevalence of VTD insufficiency or deficiency
    • Etiology of VTD deficiency and insufficiency
    • Classic effects of VTD insufficiency or deficiency on disease
    • Effects of insufficiency or deficiency on other disease states
    • Sources of VTD
    • Treatment of VTD insufficiency and deficiency
    • Conclusion
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