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Research ArticleCurrent Practice

Safety of hair products during pregnancy

Personal use and occupational exposure

Angela Chua-Gocheco, Pina Bozzo and Adrienne Einarson
Canadian Family Physician October 2008, 54 (10) 1386-1388;
Angela Chua-Gocheco
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Pina Bozzo
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Adrienne Einarson
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ABSTRACT

QUESTION Several of my pregnant patients who are hairdressers have asked me if exposure to products they use is harmful to their unborn babies. They also want to know if their pregnant clients’ personal use of hair products should be of concern.

ANSWER There is no evidence of teratogenic effects for pregnant women exposed to these products from occupational use (ie, hairdressing); however, it is recommended that pregnant hairdressers wear gloves to minimize exposure, work for no more than 35 hours per week, avoid standing for prolonged periods of time, and ensure that the salons where they work have adequate ventilation. Evidence suggests there is minimal systemic absorption of hair products, so personal use by pregnant women 3 to 4 times throughout pregnancy is not considered to be of concern.

Chemicals in hair products colour, straighten, relax, curl, and bleach hair. Hair dyes are often divided into 5 categories: gradual hair colouring, vegetable dyes, temporary dyes, semipermanent dyes, and permanent dyes.1 The most common chemicals used in permanent hair colours are phenylenediamine, 3-aminophenol, resorcinol, toluene-2,5-diaminesulphate, sodium sulfite, oleic acid, sodium hydroxide, ammonium hydroxide, propylene glycol, and isopropyl alcohol.2 The chemicals used in hair straighteners or relaxers, bleachers, and permanents include sodium hydroxide, guanidine hydroxide, ammonium thioglycolate, ammonium hydroxide, petroleum, and hydrogen peroxide.3,4

Harmful effects

Some of the chemicals used in hair products have been reported to be carcinogenic5; however, many of these chemicals have been eliminated from oxidative dye products since the early 1980s. There have been reports of hair products being associated with bladder cancer, non-Hodgkin lymphoma, multiple myeloma, acute leukemia, and neuroblastoma in offspring. However, these results have been inconsistent; most studies conducted on personal or occupational use of hair dyes showed no increased risk of cancer.6–9

Exposure during pregnancy

Experimental animal studies showed risks of teratogenicity due to some of the chemicals found in hair products, namely phenylenediamine,10 aminophenols,11–12 and ethanolamine,13 when used in very high doses. Human studies, however, show that exposure to these chemicals from hair dyes or hair products results in very limited systemic absorption, unless there are burns or abscesses on the scalp. Therefore, these chemicals are unlikely to reach the placenta in substantial amounts to cause harm to the unborn fetus.14–18

Occupational exposure

As hairdressers are exposed to chemicals that have been suggested to be teratogenic, embryotoxic, and carcinogenic, Labrèche et al attempted to measure the chemicals in the air at a number of hair salons. All chemicals measured were well below the threshold limits recommended by the American Conference of Governmental Industrial Hygienists.19 Hueber-Becker et al found that plasma levels of an oxidative hair dye were below the limit of detection in 18 hairstylists who each performed 6 hair-colour jobs in 1 day.20

A study by John et al, who examined the working conditions of pregnant women in beauty salons, found that the risk of spontaneous abortions did not increase with the number of hair-dye jobs performed per week.21

Zhu et al compared 550 hairdressers with a nonexposed group and found no statistically significant differences in fetal loss, preterm birth, small for gestational age babies, congenital malformations, or achievement of developmental milestones among their children.22 A Swedish study also did not find an increased rate of birth malformations among offspring of hairdressers when compared with those of a nonexposed group.23 In a later study, the same group found neither an increased risk of spontaneous abortion nor fertility concerns among hairdressers.24

Personal exposure

A case-control study by Blackmore-Prince et al found no increased risk for preterm delivery or low birth weight in 525 pregnant black women exposed to chemicals used to straighten and curl hair.4 Another case-control study by Rosenberg et al also did not find an association with preterm deliveries and use of hair relaxers during pregnancy in 5944 black women.25

There are no studies on occasional use of hair products during pregnancy. However, we have calculated that using these products 3 to 4 times during pregnancy would not be a concern, as they have minimal systemic absorption and women are exposed to them every 6 to 8 weeks at most during pregnancy.

Conclusion

In view of these data, use of hair products is unlikely to cause adverse fetal effects. With occupational exposure of hairdressers, the evidence suggests minimal systemic exposure to hair products; however, it is recommended that hairdressers wear gloves to minimize exposure, work for less than 35 hours per week, and avoid standing for prolonged periods of time. For the average pregnant woman, receiving hair treatments 3 to 4 times during pregnancy does not appear to increase risk of adverse effects on the fetus.

MOTHERISK

Motherisk questions are prepared by the Motherisk Team at the Hospital for Sick Children in Toronto, Ont. Dr Chua-Gocheco and Ms Bozzo are members and Ms Einarson is Assistant Director of the Motherisk Program.

Do you have questions about the effects of drugs, chemicals, radiation, or infections in women who are pregnant or breastfeeding? We invite you to submit them to the Motherisk Program by fax at 416 813-7562; they will be addressed in future Motherisk Updates.

Published Motherisk Updates are available on the College of Family Physicians of Canada website (www.cfpc.ca;) and also on the Motherisk website (www.motherisk.org;).

Footnotes

  • Competing interests

    None declared

  • Copyright© the College of Family Physicians of Canada

References

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    ZhangYSanjoseSDBracciPMMortonLMWangRBrennanPPersonal use of hair dye and the risk of certain subtypes of non-Hodgkin lymphomaAm J Epidemiol200816711132131Epub 2008 Apr 11
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    HrubyEPaarRLipplKSchwarzingerBHoferHTeratologic studies with m-phenylenediamine on ratsOesterr Forschungszent Seibersdorf19814132136
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    MankesRFStudies on the embryopathic effects of ethanolamine in Long-Evans rats: preferential embryopathy in pups contiguous with male siblings in uteroTeratog Carcinog Mutagen19866540317
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    LademannJRichterHJacobiUPatzeltAHueber-BeckerFRibaudCHuman percutaneous absorption of a direct hair dye comparing in vitro and in vivo results: implications for safety assessment and animal testingFood Chem Toxicol2008466221423Epub 2008 Feb 29
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  15. Cosmetic Ingredient Review Expert PanelFinal report on the safety assessment of HC Yellow No. 5Int J Toxicol200726Suppl 211324
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  16. Cosmetic Ingredient Review Expert PanelFinal report on the safety assessment of Basic Blue 99Int J Toxicol200726Suppl 25163
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  17. KraelingMEBronaughRLJungCTAbsorption of lawsone through human skinCutan Ocu Toxicol20072614556
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    CorbettJFMolaroRThe century of hair colourGlob Cos Ind2001169229
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    LabrècheFForestJTrottierMLalondeMSimardRCharacterization of chemical exposures in hairdressing salonsAppl Occup Environ Hyg20031812101421
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    Hueber-BeckerFNohynekGJDufourEKMeulingWJde BieATToutainHOccupational exposure of haidressers to [14C]-para-phenylenediamine-containing oxidative hair dyes: a mass balance studyFood Chem Toxicol20074511609Epub 2006 Aug 30
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Canadian Family Physician: 54 (10)
Canadian Family Physician
Vol. 54, Issue 10
1 Oct 2008
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Safety of hair products during pregnancy
Angela Chua-Gocheco, Pina Bozzo, Adrienne Einarson
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Angela Chua-Gocheco, Pina Bozzo, Adrienne Einarson
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