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LetterLetters

Punch biopsy of pigmented lesions is potentially hazardous

Brett D. Montgomery and Genevieve Marie Sadler
Canadian Family Physician January 2009; 55 (1) 24;
Brett D. Montgomery
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Genevieve Marie Sadler
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We are concerned about the recently published video by Czarnowski et al, which teaches the procedure of punch biopsy on a pigmented lesion.1 Although punch biopsy is a useful skill in primary care dermatology in some circumstances, it is generally inappropriate for the diagnosis of pigmented lesions.

Guidelines from around the world recommend excisional (rather than incisional) biopsy of suspicious pigmented lesions.2,3 Incisional biopsies, such as punch biopsies, risk sampling error. For example, areas of invasive melanoma might be present in an excisional specimen but missed in a smaller biopsy.4 Also, different but contiguous pigmented lesions commonly exist5; sampling only the benign lesion can lead to missed or delayed diagnosis of a malignancy, with potentially hazardous consequences.

Possible indications for incisional biopsy of pigmented lesions include very large lesions for which excisional biopsy would be difficult, such as large macular pigmented facial lesions.3 Even in these cases, the use of punch biopsy in diagnosing melanocytic lesions is potentially perilous, and according to British guidelines, “there is no place for incisional biopsy in primary care.”2 We recommend that incisional biopsy in primary care be limited to nonpigmented lesions and rashes.

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References

  1. ↵
    CzarnowskiCPonkaDRughaniRGeoffrionPPunch biopsy. Minor surgery video seriesCan Fam Physician2008541021
    OpenUrlFREE Full Text
  2. ↵
    RobertsDLAnsteyAVBarlowRJCoxNHNewton BishopJACorriePGUK guidelines for the management of cutaneous melanomaBr J Dermatol2002461717
    OpenUrl
  3. ↵
    Australian Cancer Network The management of cutaneous melanoma. Clinical practice guidelinesCanberra, AustraliaNational Health and Medical Research Council1999Available from: www.nhmrc.gov.au/publications/synopses/cp68syn.htmAccessed 2008 Dec 11
  4. ↵
    SomachSCTairaJWPithaJVEverettMAPigmented lesions in actinically damaged skin. Histopathologic comparison of biopsy and excisional specimensArch Dermatol1996132111297302
    OpenUrlCrossRefPubMed
  5. ↵
    DaltonSRGardnerTLLibowLFElstonDMContiguous lesions in lentigo malignaJ Am Acad Dermatol200552585962
    OpenUrlCrossRefPubMed
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Canadian Family Physician: 55 (1)
Canadian Family Physician
Vol. 55, Issue 1
1 Jan 2009
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Punch biopsy of pigmented lesions is potentially hazardous
Brett D. Montgomery, Genevieve Marie Sadler
Canadian Family Physician Jan 2009, 55 (1) 24;

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Canadian Family Physician Jan 2009, 55 (1) 24;
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