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Research ArticleResearch

Correlates of a “do not hospitalize” designation

In a sample of frail nursing home residents in Vancouver

Margaret McGregor, Dan Pare, Areta Wong, Michelle B. Cox and Penny Brasher
Canadian Family Physician November 2010; 56 (11) 1158-1164;
Margaret McGregor
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  • For correspondence: mrgret@interchange.ubc.ca
Dan Pare
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Areta Wong
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Michelle B. Cox
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Penny Brasher
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    Table 1

    Degrees of intervention

    DEGREES OF INTERVENTIONEXPLANATION
    “Do not hospitalize” designation
      • 1Supportive care—such as nursing care, relief of pain, control of fever, administration of oral fluids or intermittent oxygen, and continued management of standing chronic conditions—within the facility
    No transfer to hospital unless adequate comfort measures cannot be provided at the facility
    No CPR
      • 2Degree 1 plus therapeutic measures and medications to manage acute conditions within the limits of the facility
    No transfer to hospital unless adequate comfort measures cannot be provided at the facility
    No CPR
    “Hospitalize” designation
      • 3Degree 2 plus admission to an acute care hospital for medical or surgical treatment as indicated
    No referral to intensive care
    No CPR
      • 4Maximum therapeutic effort (as degree 3) including referral to intensive care and use of CPR if indicated
    • CPR—cardiopulmonary resuscitation.

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    Table 2

    Characteristics of the study population: Mean (SD) age was 82.6 (9.0) years.

    CHARACTERISTICS*TOTAL
    Demographic
      • Female sex, n/N (%)265/369 (72)
      • Married and partner alive, n/N (%)139/369 (38)
    Clinical and functional
      • Median (IQR) no. of Charlson comorbidities†3.0 (2.0)
      • Sudden and unexpected death, n/N (%)32/369 (9)
      • Median (IQR) no. of medications4.0 (4.0)
      • Median (IQR) no. of debilities‡2.0 (2.0)
    Use of health services
      • Visited the hospital ED in the 3 months before death, n/N (%)103/368 (28)
      • Median (IQR) no. of hospital ED visits in the 3 months before death0.0 (1.0)
      • Hospital admission in the 3 months before death, n/N (%)96/369 (26)
      • Death in facility (vs hospital), n/N (%)341/369 (92)
      • Median (IQR) no. of visits by family physician in the 3 months before death4.0 (5.0)
      • Continuity of family physician from admission to death, n/N (%)287/369 (78)
      • Median (IQR) length of stay (in weeks) from admission to extended care until death§56.1 (125.3)
      • Median (IQR) no. of weeks “at risk” of “do not hospitalize” designation from admission to extended care||2.0 (53.0)
      • Proportion of residents with “do not hospitalize” designation at time of death, n/N (%)321/367 (87)
    • SD—standard deviation, ED—emergency department, IQR—interquartile range.

    • ↵* Characteristics measured at time of death unless stated otherwise.

    • ↵† Sum of coronary artery disease, congestive heart failure, peripheral vascular disease, cerebrovascular disease, dementia, chronic pulmonary disease, connective tissue disease, ulcer disease or gastrointestinal bleed, liver disease, diabetes, hemiplegia or hemiparesis, renal disease, cancer, metastatic cancer, and AIDS.

    • ↵‡ Sum of presence of pressure ulcers, indwelling bladder catheter, wheelchair dependency, dependence on others for feeding, and requiring a mechanical lift for transfers.

    • ↵§ Residents of free-standing facilities might have entered the facilities as intermediate care residents, and entrance to extended care might have occurred at a later date.

    • ↵|| The “at risk” period was the number of weeks each resident had a “hospitalize” designation from the time of admission into extended care until death or a change to “do not hospitalize.”

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    Table 3

    Univariable and multivariable regression analyses of factors associated with “do not hospitalize” designations among residents with “hospitalize” designations on admission to extended care (n = 227)

    FACTORS*UNIVARIABLE HAZARD RATIO (95% CI)MULTIVARIABLE HAZARD RATIO (95% CI)
    Demographic
      • Age upon admission to extended care1.02 (1.01–1.02)†1.02 (1.01–1.02)†
      • Female sex1.15 (1.05–1.25)†
      • Married and partner alive1.31 (0.94–1.81)
    Clinical and functional
      • No. of Charlson comorbidities‡1.03 (0.96–1.11)
      • Sudden and unexpected death0.44 (0.20–0.97)†0.43 (0.25–0.73)†
      • No. of medications1.01 (0.94–1.09)
      • No. of debilities§0.98 (0.89–1.08)
      • Ulcer or gastrointestinal bleed||0.81 (0.50–1.31)
    Use of health services
      • No. of ED visits in 3 months before death0.85 (0.61–1.18)
      • No. of visits by family physician in 3 months before death1.00 (0.99–1.01)1.01 (1.00–1.03)†
      • Continuity of family physician from admission to death2.19 (1.38–3.47)†2.17 (1.33–3.49)†
      • Hospital-based facility1.21 (1.01–1.45)†
    • CI—confidence interval, ED—emergency department.

    • ↵* Characteristics measured at time of death unless stated otherwise.

    • ↵† Statistically significant at P ≤. 05.

    • ↵‡ Sum of coronary artery disease, congestive heart failure, peripheral vascular disease, cerebrovascular disease, dementia, chronic pulmonary disease, connective tissue disease, ulcer disease or gastrointestinal bleed, liver disease, diabetes, hemiplegia or hemiparesis, renal disease, cancer, metastatic cancer, and AIDS.

    • ↵§ Sum of presence of pressure ulcers, indwelling bladder catheter, wheelchair dependency, dependence on others for feeding, and requiring a mechanical lift for transfers.

    • ↵|| Ulcer or gastrointestinal bleed was the only Charlson comorbidity associated with the “do not hospitalize” designation at time of death in initial 2-way tests of comparison and therefore was included in Cox regression models.

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Canadian Family Physician: 56 (11)
Canadian Family Physician
Vol. 56, Issue 11
1 Nov 2010
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Correlates of a “do not hospitalize” designation
Margaret McGregor, Dan Pare, Areta Wong, Michelle B. Cox, Penny Brasher
Canadian Family Physician Nov 2010, 56 (11) 1158-1164;

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