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Research ArticlePractice

Botulinum toxin type A in pregnancy

Michael Tan, Eunji Kim, Gideon Koren and Pina Bozzo
Canadian Family Physician November 2013, 59 (11) 1183-1184;
Michael Tan
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Eunji Kim
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Gideon Koren
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Pina Bozzo
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Abstract

Question My patient received 62 units of botulinum toxin type A (BTX-A) for facial lines. Two weeks later, she found out that she was pregnant. Will this cause any harm to her fetus?

Answer Botulinum toxin is not expected to be present in systemic circulation following proper intramuscular or intradermal injection. Moreover, BTX-A, which has a high molecular weight, does not appear to cross the placenta. From the 38 pregnancies reported in the literature, including women who had botulism poisoning during pregnancy, exposure to BTX-A does not appear to increase the risk of adverse outcome in the fetus.

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Canadian Family Physician: 59 (11)
Canadian Family Physician
Vol. 59, Issue 11
1 Nov 2013
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Botulinum toxin type A in pregnancy
Michael Tan, Eunji Kim, Gideon Koren, Pina Bozzo
Canadian Family Physician Nov 2013, 59 (11) 1183-1184;

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Botulinum toxin type A in pregnancy
Michael Tan, Eunji Kim, Gideon Koren, Pina Bozzo
Canadian Family Physician Nov 2013, 59 (11) 1183-1184;
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