Skip to main content

Main menu

  • Home
  • Articles
    • Current
    • Published Ahead of Print
    • Archive
    • Supplemental Issues
    • Collections - French
    • Collections - English
  • Info for
    • Authors & Reviewers
    • Submit a Manuscript
    • Advertisers
    • Careers & Locums
    • Subscribers
    • Permissions
  • About CFP
    • About CFP
    • About the CFPC
    • Editorial Advisory Board
    • Terms of Use
    • Contact Us
  • Feedback
    • Feedback
    • Rapid Responses
    • Most Read
    • Most Cited
    • Email Alerts
  • Blogs
    • Latest Blogs
    • Blog Guidelines
    • Directives pour les blogues
  • Mainpro+ Credits
    • About Mainpro+
    • Member Login
    • Instructions
  • Other Publications
    • http://www.cfpc.ca/Canadianfamilyphysician/
    • https://www.cfpc.ca/Login/
    • Careers and Locums

User menu

  • My alerts

Search

  • Advanced search
The College of Family Physicians of Canada
  • Other Publications
    • http://www.cfpc.ca/Canadianfamilyphysician/
    • https://www.cfpc.ca/Login/
    • Careers and Locums
  • My alerts
The College of Family Physicians of Canada

Advanced Search

  • Home
  • Articles
    • Current
    • Published Ahead of Print
    • Archive
    • Supplemental Issues
    • Collections - French
    • Collections - English
  • Info for
    • Authors & Reviewers
    • Submit a Manuscript
    • Advertisers
    • Careers & Locums
    • Subscribers
    • Permissions
  • About CFP
    • About CFP
    • About the CFPC
    • Editorial Advisory Board
    • Terms of Use
    • Contact Us
  • Feedback
    • Feedback
    • Rapid Responses
    • Most Read
    • Most Cited
    • Email Alerts
  • Blogs
    • Latest Blogs
    • Blog Guidelines
    • Directives pour les blogues
  • Mainpro+ Credits
    • About Mainpro+
    • Member Login
    • Instructions
  • RSS feeds
  • Follow cfp Template on Twitter
CorrectionCorrection

Correction

Canadian Family Physician January 2019, 65 (1) 8;
  • Article
  • eLetters
  • Info & Metrics
  • PDF
Loading

Recommendations in 2 articles published in Canadian Family Physician, “Nausea and vomiting of pregnancy. Evidence-based treatment algorithm”1 and “Treatment of nausea and vomiting in pregnancy. An updated algorithm,”2 have subsequently come under critical scrutiny.3,4 These articles were not subjected to standard peer review, and Canadian Family Physician acknowledges that upon closer inspection these articles did not provide satisfactory evidence that would have justified the recommendation of doxylamine-pyridoxine as a sole first-line treatment for nausea and vomiting in pregnancy (NVP). More recent Canadian NVP guidelines have been published5; however, a subsequent re-analysis6 questions the conclusions of 1 of the studies7 cited in these guidelines to justify doxylamine-pyridoxine as a recommended first-line treatment for NVP. Additionally, for the articles in Canadian Family Physician1,2 there was an undisclosed conflict of interest with Duchesnay, the manufacturer of Diclectin, the combination of doxylamine-pyridoxine. Canadian Family Physician encourages readers to interpret previously published NVP recommendations with caution. Readers are also referred to the commentary “Motherisk and Canadian Family Physician” in the January 2017 issue of Canadian Family Physician.8

  • Copyright© the College of Family Physicians of Canada

References

  1. 1.↵
    1. Levichek Z,
    2. Atanackovic G,
    3. Oepkes D,
    4. Maltepe C,
    5. Einarson A,
    6. Magee L,
    7. et al
    . Nausea and vomiting of pregnancy. Evidence-based treatment algorithm. Can Fam Physician 2002;48:267-8, 277.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    1. Einarson A,
    2. Maltepe C,
    3. Boskovic R,
    4. Koren G
    . Treatment of nausea and vomiting in pregnancy. An updated algorithm. Can Fam Physician 2007;53:2109-11.
    OpenUrlAbstract/FREE Full Text
  3. 3.↵
    1. Chin JWS,
    2. Gregor S,
    3. Persaud N
    . Re-analysis of safety data supporting doxylamine use for nausea and vomiting of pregnancy. Am J Perinatol 2014;31(8):701-10. Epub 2013 Dec 9.
    OpenUrl
  4. 4.↵
    1. Persaud N,
    2. Chin J,
    3. Walker M
    . Should doxylamine-pyridoxine be used for nausea and vomiting of pregnancy? J Obstet Gynaecol Can 2014;36(4):343-8.
    OpenUrl
  5. 5.↵
    1. Campbell K,
    2. Rowe H,
    3. Azzam H,
    4. Lane CA
    . The management of nausea and vomiting of pregnancy. J Obstet Gynaecol Can 2016;38(12):1127-37.
    OpenUrl
  6. 6.↵
    1. Persaud N,
    2. Meaney C,
    3. El-Emam K,
    4. Moineddin R,
    5. Thorpe K
    . Doxylamine-pyridoxine for nausea and vomiting of pregnancy randomized placebo controlled trial: prespecified analyses and reanalysis. PLoS One 2018;13(1):e0189978.
    OpenUrl
  7. 7.↵
    1. Koren G,
    2. Clark S,
    3. Hankins GD,
    4. Caritis SN,
    5. Miodovnik M,
    6. Umans JG,
    7. et al
    . Effectiveness of delayed-release doxylamine and pyridoxine for nausea and vomiting of pregnancy: a randomized placebo controlled trial. Am J Obstet Gynecol 2010;203(6):571.e1-7. Epub 2010 Sep 16.
    OpenUrlPubMed
  8. 8.↵
    1. Pimlott N,
    2. Kvern B,
    3. Woollard R
    . Motherisk and Canadian Family Physician. Can Fam Physician 2017;63:13-4. (Eng), e1–2 (Fr).
    OpenUrlFREE Full Text
PreviousNext
Back to top

In this issue

Canadian Family Physician: 65 (1)
Canadian Family Physician
Vol. 65, Issue 1
1 Jan 2019
  • Table of Contents
  • About the Cover
  • Index by author
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on The College of Family Physicians of Canada.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Correction
(Your Name) has sent you a message from The College of Family Physicians of Canada
(Your Name) thought you would like to see the The College of Family Physicians of Canada web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Correction
Canadian Family Physician Jan 2019, 65 (1) 8;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Respond to this article
Share
Correction
Canadian Family Physician Jan 2019, 65 (1) 8;
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • References
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

  • Nausea and vomiting of pregnancy. Evidence-based treatment algorithm.
  • Treatment of nausea and vomiting in pregnancy
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Correction
  • Correction
  • Correction
Show more Correction

Similar Articles

Navigate

  • Home
  • Current Issue
  • Archive
  • Collections - English
  • Collections - Française

For Authors

  • Authors and Reviewers
  • Submit a Manuscript
  • Permissions
  • Terms of Use

General Information

  • About CFP
  • About the CFPC
  • Advertisers
  • Careers & Locums
  • Editorial Advisory Board
  • Subscribers

Journal Services

  • Email Alerts
  • Twitter
  • RSS Feeds

Copyright © 2021 by The College of Family Physicians of Canada

Powered by HighWire