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Hypoglycemia in type 2 diabetes

It is common, so what strategies can minimize the risk?

Marlys LeBras and Tessa Laubscher
Canadian Family Physician January 2021; 67 (1) 35-38; DOI: https://doi.org/10.46747/cfp.670135

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  • Table 1.

    Head-to-head overall hypoglycemia rates among basal insulins

    COMPARATOROVERALL HYPOGLYCEMIA RESULTS
    CADTH meta-analysis21

    • NPH: 55.9%

    • Glargine: 47.2%

    • NNT = 12 over 6-12 mo

    EDITION meta-analysis24

    • 100 units/mL glargine: 72.8%

    • 300 units/mL glargine: 66.5%

    • NNT = 16 over 6 mo

    SWITCH 2 trial25

    • 100 units/mL glargine: 31.6%

    • Degludec: 22%

    • NNT = 11 over 7 mo

    • CADTH—Canadian Agency for Drugs and Technologies in Health, NNT—number needed to treat, NPH—neutral protamine Hagedorn.

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Hypoglycemia in type 2 diabetes
Marlys LeBras, Tessa Laubscher
Canadian Family Physician Jan 2021, 67 (1) 35-38; DOI: 10.46747/cfp.670135
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