TY - JOUR T1 - Taking ACE inhibitors during pregnancy. Is it safe? JF - Canadian Family Physician JO - Can Fam Physician SP - 1047 LP - 1049 VL - 48 IS - 6 AU - Savithiri Ratnapalan AU - Gideon Koren Y1 - 2002/06/01 UR - http://www.cfp.ca/content/48/6/1047.abstract N2 - QUESTION: A pregnant patient is taking enalapril for primary hypertension. How safe are angiotension-converting enzyme inhibitors (ACEI) during pregnancy? ANSWER: Evidence of whether ACEIs cause problems during the first trimester of pregnancy is reassuring. There is evidence that they cause severe renal and other problems during the second and third trimesters, however. These drugs should be avoided during pregnancy. ER -