PT - JOURNAL ARTICLE AU - Koren, Gideon TI - Breakthrough in treating gestational diabetes mellitus. DP - 2004 Jul 01 TA - Canadian Family Physician PG - 987--987 VI - 50 IP - 7 4099 - http://www.cfp.ca/content/50/7/987.short 4100 - http://www.cfp.ca/content/50/7/987.full SO - Can Fam Physician2004 Jul 01; 50 AB - QUESTION: I practise in a remote community in Manitoba. Quite a few of my patients experience gestational diabetes. Their compliance with the insulin regimen is abysmal. Can I give them an oral medication? ANSWER: Recent studies have indicated that glyburide does not cross the human placenta and that its effectiveness and safety profiles are similar to those of insulin.