RT Journal Article SR Electronic T1 Carpal tunnel syndrome and vitamin B6 JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 1161 OP 1162 VO 53 IS 7 A1 Ryan-Harshman, Milly A1 Aldoori, Walid YR 2007 UL http://www.cfp.ca/content/53/7/1161.abstract AB QUESTION A 42-year-old woman with carpal tunnel syndrome tells you she has started taking a vitamin B6 supplement to relieve her symptoms. Her work in an automotive parts department involves both lifting moderately heavy packages and typing at a computer terminal. What does the research indicate about vitamin B6 as a treatment option, and what health issues should you discuss with this patient? ANSWER Although its effectiveness is controversial, vitamin B6 is often used as a conservative and adjunct therapy in treatment of carpal tunnel syndrome. Many patients attempt to treat their symptoms with vitamin B6 on their own. Vitamin B6 at less than 200 mg daily is not likely to cause any adverse effects, but patients should be monitored for changes in symptoms, particularly when high doses are taken over long periods.