TY - JOUR T1 - Use of diuretics during pregnancy JF - Canadian Family Physician JO - Can Fam Physician SP - 44 LP - 45 VL - 55 IS - 1 AU - Mosa’b Al-Balas AU - Pina Bozzo AU - Adrienne Einarson Y1 - 2009/01/01 UR - http://www.cfp.ca/content/55/1/44.abstract N2 - QUESTION Several of my pregnant patients use diuretics for hypertension. I have heard that diuretics cannot be used in pregnancy because of the reduction of plasma volume and the potential for decreasing placental perfusion, as well as a possible diabetogenic effect. ANSWER Many studies—including a meta-analysis of almost 7000 neonates exposed to diuretics during pregnancy—did not find an increased risk of adverse effects, such as birth defects, fetal growth restriction, thrombocytopenia, or diabetes, among neonates exposed to diuretics in utero. ER -