RT Journal Article SR Electronic T1 Twenty-five years of counseling family physicians JF Canadian Family Physician JO Can Fam Physician FD The College of Family Physicians of Canada SP 655 OP 656 VO 56 IS 7 A1 Koren, Gideon A1 Einarson, Adrienne YR 2010 UL http://www.cfp.ca/content/56/7/655.abstract AB QUESTION In 1985, for the first time I asked Motherisk for advice regarding a pregnant patient who, unaware of her pregnancy, had taken tetracycline. I was very concerned, as was my patient, who was ready to terminate a wanted pregnancy for fear that she had harmed her baby. As a direct result of your advice, this “fetus” is now a happy 25-year-old mother of a healthy son. Your answer to me was as follows: This woman was exposed to tetracycline long before the teeth buds were formed; therefore, there was no apparent fetal risk. What do you think is some of the most important information you have given to practising family physicians over the past 25 years? ANSWER Unfortunately, too many decisions regarding management of pregnant women are based on misinformation or misconceptions of teratogenic risk. It is critical to base therapeutic decisions regarding exposures during pregnancy on balancing risks of untreated maternal disease with the existing evidence-based information on fetal safety.