PT  - JOURNAL ARTICLE
AU  - Marie-Hélène Irvine
AU  - Adrienne Einarson
AU  - Pina Bozzo
TI  - Prophylactic use of antimalarials during pregnancy
DP  - 2011 Nov 01
TA  - Canadian Family Physician
PG  - 1279--1281
VI  - 57
IP  - 11
4099  - http://www.cfp.ca/content/57/11/1279.short
4100  - http://www.cfp.ca/content/57/11/1279.full
SO  - Can Fam Physician2011 Nov 01; 57
AB  - Question Some of my pregnant patients wish to travel to malaria-endemic regions. Are there medications that can be used safely during pregnancy for malaria prophylaxis? Answer Pregnant women should avoid travel to malaria-endemic areas if possible. However, if travel cannot be avoided, measures to prevent mosquito bites, along with an effective chemoprophylaxis regimen, should be implemented. Chloroquine or hydroxychloroquine are considered safe to use in all trimesters of pregnancy. Mefloquine is the agent of choice for chloroquine-resistant areas, and evidence suggests it is not associated with an increased risk to the fetus. Although the atovaquone-proguanil drug combination is not currently recommended for use during pregnancy, limited data suggest that it is not harmful to the fetus. Doxycycline and primaquine are not recommended during pregnancy.